A High-Throughput Chemical Screen Reveals That Harmine-Mediated Inhibition of DYRK1A Increases Human Pancreatic Beta Cell Replication

Nature Medicine - United Kingdom
doi 10.1038/nm.3820
Full Text
Abstract

Available in full text

Date
Authors
Publisher

Springer Science and Business Media LLC

Related search

High-Throughput Live-Cell Imaging Reveals Differential Inhibition of Tumor Cell Proliferation by Human Fibroblasts

International Journal of Cancer
Cancer ResearchOncology
2010English

Inhibition of DYRK1A Stimulates Human Β-Cell Proliferation

Diabetes
Internal MedicineEndocrinologyMetabolismDiabetes
2016English

Combined Inhibition of DYRK1A, SMAD, and Trithorax Pathways Synergizes to Induce Robust Replication in Adult Human Beta Cells

Cell Metabolism
Cell BiologyMolecular BiologyPhysiology
2019English

High-Throughput Cell-Based Screen for Chemicals That Inhibit Infection by Simian Virus 40 and Human Polyomaviruses

Journal of Virology
Insect ScienceImmunologyMicrobiologyVirology
2009English

High-Throughput Screen Using a Single-Cell Tyrosine Phosphatase Assay Reveals Biologically Active Inhibitors of Tyrosine Phosphatase CD45

Proceedings of the National Academy of Sciences of the United States of America
Multidisciplinary
2012English

Towards a Model of the Human Pancreatic Beta Cell

Biophysical Journal
Biophysics
2019English

Development of a High-Throughput Functional Screen Using Nanowell-Assisted Cell Patterning

Small
Materials ScienceNanoscienceEngineeringBiomaterialsMedicineBiotechnologyNanotechnologyChemistry
2015English

A Multi-Lineage Screen Reveals mTORC1 Inhibition Enhances Human Pluripotent Stem Cell Mesendoderm and Blood Progenitor Production

Stem Cell Reports
BiochemistryGeneticsDevelopmental BiologyCell Biology
2016English

A High-Throughput Phenotypic Screen of Cytotoxic T Lymphocyte Lytic Granule Exocytosis Reveals Candidate Immunosuppressants

Journal of Biomolecular Screening
Molecular MedicinePharmacologyBiochemistryAnalytical ChemistryBiotechnologyDrug Discovery
2015English

Amanote Research

Note-taking for researchers

Follow Amanote

© 2024 Amaplex Software S.P.R.L. All rights reserved.

Privacy PolicyRefund Policy