Selective Inhibition of HDAC1 by Macrocyclic Polypeptide for the Treatment of Glioblastoma: A Binding Mechanistic Analysis Based on Molecular Dynamics

Frontiers in Molecular Biosciences - Switzerland
doi 10.3389/fmolb.2020.00041
Full Text
Abstract

Available in full text

Date
Authors
Publisher

Frontiers Media SA

Related search

Autoencoder-Based Detection of Dynamic Allostery Triggered by Ligand Binding Based on Molecular Dynamics

English

Selective Inhibition of IRE1 Signalling Mediated by MKC9989: New Insights From Molecular Docking and Molecular Dynamics Simulations

ChemistrySelect
Chemistry
2019English

A Small Molecular Scaffold for Selective Inhibition of Wip1 Phosphatase

ChemMedChem
Organic ChemistryMolecular MedicinePharmacologyBiochemistryToxicologyDrug DiscoveryPharmaceutics
2008English

Inhibition of the Activity of HIV-1 Protease Through Antibody Binding and Mutations Probed by Molecular Dynamics Simulations

Scientific Reports
Multidisciplinary
2020English

Mechanism of Selective VEGF-A Binding by Neuropilin-1 Reveals a Basis for Specific Ligand Inhibition

PLoS ONE
Multidisciplinary
2012English

Molecular Basis for the Inhibition of the Methyl-Lysine Binding Function of 53BP1 by TIRR

Nature Communications
AstronomyGeneticsMolecular BiologyBiochemistryChemistryPhysics
2018English

Exploration of Binding and Inhibition Mechanism of a Small Molecule Inhibitor of Influenza Virus H1N1 Hemagglutinin by Molecular Dynamics Simulation

Scientific Reports
Multidisciplinary
2017English

Details of GABA Binding to the GABA-A Receptor Revealed by Molecular Dynamics

Biophysical Journal
Biophysics
2013English

A Mechanistic PK/PD Model of Factor D Inhibition in Cynomolgus Monkeys by Lampalizumab for the Treatment of Geographic Atrophy

Journal of Pharmacology and Experimental Therapeutics
Molecular MedicinePharmacology
2015English

Amanote Research

Note-taking for researchers

Follow Amanote

© 2025 Amaplex Software S.P.R.L. All rights reserved.

Privacy PolicyRefund Policy