Evading the STING: LKB1 Loss Leads to STING Silencing and Immune Escape in KRAS-Mutant Lung Cancers

Cancer Discovery - United States
doi 10.1158/2159-8290.cd-18-1286
Full Text
Abstract

Available in full text

Categories
Oncology
Date
Authors
Publisher

American Association for Cancer Research (AACR)

Related search

Suppression of STING Associated With LKB1 Loss in KRAS-driven Lung Cancer

Cancer Discovery
Oncology
2018English

Immunohistochemical Loss of LKB1 Is a Biomarker for More Aggressive Biology in KRAS-Mutant Lung Adenocarcinoma

Clinical Cancer Research
Cancer ResearchOncology
2015English

A Sting in the Tail?

Learned Publishing
Communication
2018English

KRAS Mutation-Induced Upregulation of PD-L1 Mediates Immune Escape in Human Lung Adenocarcinoma

Cancer Immunology, Immunotherapy
Cancer ResearchMedicineOncologyAllergyImmunology
2017English

An Antiviral STING

Lab Animal
Animal ScienceZoologyVeterinary
2018English

KDM5 Histone Demethylases Repress Immune Response via Suppression of STING

PLoS Biology
ImmunologyMolecular BiologyGeneticsBiochemistryMicrobiology Biological SciencesAgriculturalNeuroscience
2018English

Effective Use of PI3K and MEK Inhibitors to Treat Mutant Kras G12D and PIK3CA H1047R Murine Lung Cancers

Nature Medicine
BiochemistryMedicineGeneticsMolecular Biology
2008English

Prevalence and Specificity of LKB1 Genetic Alterations in Lung Cancers

Oncogene
Cancer ResearchGeneticsMolecular Biology
2007English

Restriction by SAMHD1 Limits cGAS/STING-Dependent Innate and Adaptive Immune Responses to HIV-1

Cell Reports
BiochemistryGeneticsMolecular Biology
2016English

Amanote Research

Note-taking for researchers

Follow Amanote

© 2024 Amaplex Software S.P.R.L. All rights reserved.

Privacy PolicyRefund Policy