(PDF) Modeling and Mutational Analysis of the Binding Mode

Modeling and Mutational Analysis of the Binding Mode for the Multimodal Antidepressant Drug Vortioxetine to the Human 5-Ht3a Receptor

Molecular Pharmacology - United States

doi 10.1124/mol.118.113530

Full Text

Open PDF

Abstract

Available in full text

Date

September 26, 2018

Authors

Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Related search

Molecular Insight Into the Agonist Properties of the Multimodal Antidepressant Vortioxetine in Human 5-Ht3a Receptors

Biophysical Journal

Biophysics

2019

English

A Systematic Mutational Analysis of Hormone-Binding Determinants in the Human Growth Hormone Receptor.

Proceedings of the National Academy of Sciences of the United States of America

Multidisciplinary

1991

English

Detailed Analysis of the Binding Mode of Vanilloids to Transient Receptor Potential Vanilloid Type I (TRPV1) by a Mutational and Computational Study

PLoS ONE

Multidisciplinary

2016

English

Structural and Functional Characterization of the Aryl Hydrocarbon Receptor Ligand Binding Domain by Homology Modeling and Mutational Analysis

English

Structural and Functional Characterization of the Aryl Hydrocarbon Receptor Ligand Binding Domain by Homology Modeling and Mutational Analysis

English

Mutational Analysis of the Transferrin Receptor Reveals Overlapping HFE and Transferrin Binding Sites

Journal of Molecular Biology

English

Differentiated Effects of the Multimodal Antidepressant Vortioxetine on Sleep Architecture: Part 2, Pharmacological Interactions in Rodents Suggest a Role of Serotonin-3 Receptor Antagonism

Journal of Psychopharmacology

English

From Target to Drug: Generative Modeling for the Multimodal Structure-Based Ligand Design

English

Transient Expression and Mutational Analysis of the Rotavirus Intracellular Receptor: The C-Terminal Methionine Residue Is Essential for Ligand Binding.

English

Amanote Research

Modeling and Mutational Analysis of the Binding Mode for the Multimodal Antidepressant Drug Vortioxetine to the Human 5-Ht3a Receptor

Molecular Pharmacology - United States

doi 10.1124/mol.118.113530

Full Text

Abstract

Categories

Date

Authors

Publisher

Related search

Molecular Insight Into the Agonist Properties of the Multimodal Antidepressant Vortioxetine in Human 5-Ht3a Receptors

A Systematic Mutational Analysis of Hormone-Binding Determinants in the Human Growth Hormone Receptor.

Detailed Analysis of the Binding Mode of Vanilloids to Transient Receptor Potential Vanilloid Type I (TRPV1) by a Mutational and Computational Study

Structural and Functional Characterization of the Aryl Hydrocarbon Receptor Ligand Binding Domain by Homology Modeling and Mutational Analysis

Structural and Functional Characterization of the Aryl Hydrocarbon Receptor Ligand Binding Domain by Homology Modeling and Mutational Analysis

Mutational Analysis of the Transferrin Receptor Reveals Overlapping HFE and Transferrin Binding Sites

Differentiated Effects of the Multimodal Antidepressant Vortioxetine on Sleep Architecture: Part 2, Pharmacological Interactions in Rodents Suggest a Role of Serotonin-3 Receptor Antagonism

From Target to Drug: Generative Modeling for the Multimodal Structure-Based Ligand Design

Transient Expression and Mutational Analysis of the Rotavirus Intracellular Receptor: The C-Terminal Methionine Residue Is Essential for Ligand Binding.