(PDF) Both Ligand- And Cell-Specific Parameters Control

Both Ligand- And Cell-Specific Parameters Control Ligand Agonism in a Kinetic Model of G Protein–Coupled Receptor Signaling

PLoS Computational Biology - United States

doi 10.1371/journal.pcbi.0030006

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Date

January 1, 2007

Authors

Tamara L. Kinzer-Ursem

Jennifer J. Linderman

Publisher

Public Library of Science (PLoS)

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Both Ligand- And Cell-Specific Parameters Control Ligand Agonism in a Kinetic Model of G Protein–Coupled Receptor Signaling

PLoS Computational Biology - United States

doi 10.1371/journal.pcbi.0030006

Full Text

Abstract

Categories

Date

Authors

Publisher

Related search

Structural Determinants for Ligand-Receptor Conformational Selection in a Peptide G Protein-Coupled Receptor

Dynamical Binding Modes Determine Agonistic and Antagonistic Ligand Effects in the Prostate-Specific G-Protein Coupled Receptor (PSGR)

Peptide Ligand Recognition by G Protein-Coupled Receptors

Identification of Specific Transmembrane Residues and Ligand-Induced Interface Changes Involved in Homo-Dimer Formation of a Yeast G Protein-Coupled Receptor

Double-Mutant Cycle Scanning of the Interaction of a Peptide Ligand and Its G Protein-Coupled Receptor†

Ligand and Structure-Based Methodologies for the Prediction of the Activity of G Protein-Coupled Receptor Ligands

CC Chemokine Ligand-2 Synergizes With the Nonchemokine G Protein-Coupled Receptor Ligand fMLP in Monocyte Chemotaxis, and It Cooperates With the TLR Ligand LPS via Induction of CXCL8

Human Serotonin 5-Ht2c G Protein-Coupled Receptor Homology Model From the Β2 Adrenoceptor Structure: Ligand Docking and Mutagenesis Studies

Regulation of G Protein-Coupled Receptor Signaling: Specific Dominant-Negative Effects of Melanocortin 2 Receptor Accessory Protein 2