Β-Secretase Cleavage at Amino Acid Residue 34 in the Amyloid Β Peptide Is Dependent Upon Γ-Secretase Activity

Journal of Biological Chemistry - United States
doi 10.1074/jbc.m209859200
Full Text
Abstract

Available in full text

Date
Authors
Publisher

American Society for Biochemistry & Molecular Biology (ASBMB)

Related search

The Role of Γ-Secretase Activating Protein (GSAP) and Imatinib in the Regulation of Γ-Secretase Activity and Amyloid-Β Generation

Journal of Biological Chemistry
BiochemistryCell BiologyMolecular Biology
2012English

Intramembrane Proteolysis of Β-Amyloid Precursor Protein by Γ-Secretase Is an Unusually Slow Process

Biophysical Journal
Biophysics
2015English

Presenilin-Dependent Γ-Secretase-Like Intramembrane Cleavage of ErbB4

Journal of Biological Chemistry
BiochemistryCell BiologyMolecular Biology
2001English

Equimolar Production of Amyloid Β-Protein and Amyloid Precursor Protein Intracellular Domain From Β-Carboxyl-Terminal Fragment by Γ-Secretase

Journal of Biological Chemistry
BiochemistryCell BiologyMolecular Biology
2006English

The Transmembrane Aspartates in Presenilin 1 and 2 Are Obligatory for Γ-Secretase Activity and Amyloid Β-Protein Generation

Journal of Biological Chemistry
BiochemistryCell BiologyMolecular Biology
2000English

Β-Arrestin 2 Regulates Aβ Generation and Γ-Secretase Activity in Alzheimer’s Disease

Molecular Neurodegeneration
Molecular NeuroscienceNeurologyMolecular BiologyCellular
2013English

An Anti-Parkinson’s Disease Drug via Targeting Adenosine A2A Receptor Enhances Amyloid-Β Generation and Γ-Secretase Activity

PLoS ONE
Multidisciplinary
2016English

Loss of Function ofATXN1Increases Amyloid Β-Protein Levels by Potentiating Β-Secretase Processing of Β-Amyloid Precursor Protein

Journal of Biological Chemistry
BiochemistryCell BiologyMolecular Biology
2010English

Identification of Two Novel Synaptic Γ-Secretase Associated Proteins That Affect Amyloid Β-Peptide Levels Without Altering Notch Processing

Neurochemistry International
Molecular NeuroscienceCell BiologyCellular
2012English

Amanote Research

Note-taking for researchers

Follow Amanote

© 2024 Amaplex Software S.P.R.L. All rights reserved.

Privacy PolicyRefund Policy