Pancreatic Alpha Cells in Diabetic Rats Express Active GLP-1 Receptor: Endosomal Co-Localization of GLP-1/GLP-1R Complex Functioning Through Intra-Islet Paracrine Mechanism

Scientific Reports- United Kingdom

doi 10.1038/s41598-018-21751-w

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February 27, 2018

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Springer Science and Business Media LLC

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Pancreatic Alpha Cells in Diabetic Rats Express Active GLP-1 Receptor: Endosomal Co-Localization of GLP-1/GLP-1R Complex Functioning Through Intra-Islet Paracrine Mechanism

Scientific Reports- United Kingdom

Full Text

Abstract

Categories

Date

Authors

Publisher

Related search

Glucagon-Like Peptide-1 Receptor (GLP1R; GLP-1R)

Chronic Exposure to GLP-1 Increases GLP-1 Synthesis and Release in a Pancreatic Alpha Cell Line (Α-Tc1): Evidence of a Direct Effect of GLP-1 on Pancreatic Alpha Cells

GLP-1 Receptor Signaling Protects Pancreatic Beta Cells in Intraportal Islet Transplant by Inhibiting Apoptosis

Evidence for Paracrine/Autocrine Regulation of GLP-1-producing Cells

Blockade of Cannabinoid 1 Receptor Improves GLP-1R Mediated Insulin Secretion in Mice

Value of the Radiolabelled GLP-1 Receptor Antagonist Exendin(9–39) for Targeting of GLP-1 Receptor-Expressing Pancreatic Tissues in Mice and Humans

The Privileged Position of GLP-1 in Diabetic Nephropathy

Glucagon-Like Peptide-1 Receptor (GLP-1R) Signaling Ameliorates Dysfunctional Immunity in COPD Patients

The Cardiovascular Effects of GLP-1 Receptor Agonists