Pharmacological LRRK2 Kinase Inhibition Induces LRRK2 Protein Destabilization and Proteasomal Degradation

Scientific Reports - United Kingdom
doi 10.1038/srep33897
Full Text
Abstract

Available in full text

Date
Authors
Publisher

Springer Science and Business Media LLC

Related search

mTOR Independent Alteration in ULK1 Ser758 Phosphorylation Following Chronic LRRK2 Kinase Inhibition

Bioscience Reports
BiochemistryCell BiologyMolecular BiologyBiophysics
2018English

LRRK2 Kinase Regulates Α-Synuclein Propagation via RAB35 Phosphorylation

Nature Communications
AstronomyGeneticsMolecular BiologyBiochemistryChemistryPhysics
2018English

Rab29 Activation of the Parkinson's Disease‐associated LRRK2 Kinase

EMBO Journal
ImmunologyMolecular BiologyBiochemistryMicrobiology NeuroscienceMedicineGenetics
2019English

Selective LRRK2 Kinase Inhibition Reduces Phosphorylation of Endogenous Rab10 and Rab12 in Human Peripheral Mononuclear Blood Cells

Scientific Reports
Multidisciplinary
2017English

LRRK2 G2019S Mutation Attenuates Microglial Motility by Inhibiting Focal Adhesion Kinase

Nature Communications
AstronomyGeneticsMolecular BiologyBiochemistryChemistryPhysics
2015English

Pathogenic LRRK2 Regulates Ciliation Probability Upstream of Tau Tubulin Kinase 2

2020English

LRRK2 Pathobiology in Parkinson's Disease

Journal of Neurochemistry
BiochemistryMolecular NeuroscienceCellular
2014English

Screening for Chemical Modulators for LRRK2

Biochemical Society Transactions
Biochemistry
2016English

Identification and Characterization of a Leucine-Rich Repeat Kinase 2 (LRRK2) Consensus Phosphorylation Motif

PLoS ONE
Multidisciplinary
2010English

Amanote Research

Note-taking for researchers

Follow Amanote

© 2024 Amaplex Software S.P.R.L. All rights reserved.

Privacy PolicyRefund Policy