The Tumor Suppressor Gene hCDC4 Is Frequently Mutated in Human T-Cell Acute Lymphoblastic Leukemia With Functional Consequences for Notch Signaling

Cancer Research - United States
doi 10.1158/0008-5472.can-06-4381
Full Text
Abstract

Available in full text

Date
Authors
Publisher

American Association for Cancer Research (AACR)

Related search

Tcrδtranslocations That Delete theBcl11bhaploinsufficient Tumor Suppressor Gene Promote Atm-Deficient T Cell Acute Lymphoblastic Leukemia

Cell Cycle
MedicineDevelopmental BiologyCell BiologyMolecular Biology
2014English

NOTCH1 Signaling Promotes Human T-Cell Acute Lymphoblastic Leukemia Initiating Cell Regeneration in Supportive Niches

PLoS ONE
Multidisciplinary
2012English

Inhibition of Notch Signaling Enhances Chemosensitivity in B Cell Precursor Acute Lymphoblastic Leukemia.

Cancer Research
Cancer ResearchOncology
2018English

Pre-T Cell Receptor Signaling Drives Leukemogenesis and Is a Therapeutic Target in T Cell Acute Lymphoblastic Leukemia

Hematological Oncology
MedicineCancer ResearchOncologyHematology
2019English

Notch-1 Mutations Are Secondary Events in Some Patients With T-Cell Acute Lymphoblastic Leukemia

Clinical Cancer Research
Cancer ResearchOncology
2007English

Epigenetic Inactivation of Notch-Hes Pathway in Human B-Cell Acute Lymphoblastic Leukemia

PLoS ONE
Multidisciplinary
2013English

Alteration in Expression of miR-32 and FBXW7 Tumor Suppressor in Plasma Samples of Patients With T-Cell Acute Lymphoblastic Leukemia

Cancer Management and Research
Oncology
2020English

The Normal Epithelial Cell-Specific 1 (NES1) Gene, a Candidate Tumor Suppressor Gene on Chromosome 19q13.3–4, Is Downregulated by Hypermethylation in Acute Lymphoblastic Leukemia

Leukemia
Cancer ResearchOncologyAnesthesiologyPain MedicineHematology
2003English

Aberrant Signaling in T-Cell Acute Lymphoblastic Leukemia: Biological and Therapeutic Implications

Brazilian Journal of Medical and Biological Research
ImmunologyCell BiologyPharmacologyBiochemistryBiophysicsNeuroscienceMedicineToxicologyPhysiologyPharmaceutics
2008English

Amanote Research

Note-taking for researchers

Follow Amanote

© 2024 Amaplex Software S.P.R.L. All rights reserved.

Privacy PolicyRefund Policy