The FGFR1 V561M Gatekeeper Mutation Drives AZD4547 Resistance Through STAT3 Activation and EMT

Molecular Cancer Research - United States
doi 10.1158/1541-7786.mcr-18-0429
Full Text
Abstract

Available in full text

Date
Authors
Publisher

American Association for Cancer Research (AACR)

Related search

Activation of Tyrosine Kinases by Mutation of the Gatekeeper Threonine

Nature Structural and Molecular Biology
Structural BiologyMolecular Biology
2008English

STAT3 Mutation Is Associated With STAT3 Activation in CD30+ ALK− ALCL

Cancers
Cancer ResearchOncology
2020English

Activation of Stat3 by Heregulin/ErbB-2 Through the Co-Option of Progesterone Receptor Signaling Drives Breast Cancer Growth

Molecular and Cellular Biology
Cell BiologyMolecular Biology
2008English

Correction: Translating the Therapeutic Potential of AZD4547 in FGFR1-Amplified Non-Small Cell Lung Cancer Through the Use of Patient-Derived Tumor Xenograft Models

Clinical Cancer Research
Cancer ResearchOncology
2013English

STAT3 Activation

JAK-STAT
2013English

SHP-1 Reverses Trastuzumab Resistance and Migration in HER2-positive Breast Cancer Cells Through the Stat3/P-Stat3 Pathway

Biomedical Research
2018English

Leukemia Inhibitory Factor Inhibits Neuronal Terminal Differentiation Through STAT3 Activation

Proceedings of the National Academy of Sciences of the United States of America
Multidisciplinary
2002English

RRAD Promotes EGFR-Mediated STAT3 Activation and Induces Temozolomide Resistance of Malignant Glioblastoma

Molecular Cancer Therapeutics
Cancer ResearchOncology
2014English

Oncogenic Activation of Stat3 Pathway Drives Pd-L1 Expression in Natural Killer/T Cell Lymphoma

Hematological Oncology
MedicineCancer ResearchOncologyHematology
2017English

Amanote Research

Note-taking for researchers

Follow Amanote

© 2024 Amaplex Software S.P.R.L. All rights reserved.

Privacy PolicyRefund Policy