Inhibition of Topoisomerase IIA (Top2α) Induces Telomeric DNA Damage and T Cell Dysfunction During Chronic Viral Infection

Cell Death and Disease - United Kingdom
doi 10.1038/s41419-020-2395-2
Full Text
Abstract

Available in full text

Date
Authors
Publisher

Springer Science and Business Media LLC

Related search

Telomeric DNA Damage by Topoisomerase I

Journal of Biological Chemistry
BiochemistryCell BiologyMolecular Biology
2004English

Type I Interferons Suppress Viral Replication but Contribute to T Cell Depletion and Dysfunction During Chronic HIV-1 Infection

JCI insight
Medicine
2017English

DNA Damage Response Inhibition at Dysfunctional Telomeres by Modulation of Telomeric DNA Damage Response RNAs

Nature Communications
AstronomyGeneticsMolecular BiologyBiochemistryChemistryPhysics
2017English

Memory CD8 T-Cell Differentiation During Viral Infection

Journal of Virology
Insect ScienceImmunologyMicrobiologyVirology
2004English

Role of Thymic Output in Regulating CD8 T-Cell Homeostasis During Acute and Chronic Viral Infection

Journal of Virology
Insect ScienceImmunologyMicrobiologyVirology
2005English

Therapeutic Conserved Elements (CE) DNA Vaccine Induces Strong T-Cell Responses Against Highly Conserved Viral Sequences During Simian-Human Immunodeficiency Virus Infection

Human Vaccines and Immunotherapeutics
MedicineAllergyImmunologyPharmacology
2018English

Chromatin at the Intersection of Viral Infection and DNA Damage

Biochimica et Biophysica Acta - Gene Regulatory Mechanisms
BiochemistryGeneticsStructural BiologyMolecular BiologyBiophysics
2010English

Cell-Intrinsic IL-27 and Gp130 Cytokine Receptor Signaling Regulates Virus-Specific CD4+ T Cell Responses and Viral Control During Chronic Infection

Immunity
Infectious DiseasesAllergyImmunology
2013English

Both Telomeric and Non-Telomeric DNA Damage Are Determinants of Mammalian Cellular Senescence

Epigenetics and Chromatin
GeneticsMolecular Biology
2008English

Amanote Research

Note-taking for researchers

Follow Amanote

© 2024 Amaplex Software S.P.R.L. All rights reserved.

Privacy PolicyRefund Policy