Exploring the Effects of Active Site Constraints on HIV-1 Reverse Transcriptase DNA Polymerase Fidelity

Journal of Biological Chemistry - United States
doi 10.1074/jbc.m207854200
Full Text
Abstract

Available in full text

Date
Authors
Publisher

American Society for Biochemistry & Molecular Biology (ASBMB)

Related search

The P66 Immature Precursor of HIV-1 Reverse Transcriptase

Proteins: Structure, Function and Genetics
BiochemistryStructural BiologyMolecular Biology
2014English

Increased Polymerase Fidelity of E89G, a Nucleoside Analog-Resistant Variant of Human Immunodeficiency Virus Type 1 Reverse Transcriptase.

Journal of Virology
Insect ScienceImmunologyMicrobiologyVirology
1996English

Human DNA Polymerase Η Has Reverse Transcriptase Activity in Cellular Environments

Journal of Biological Chemistry
BiochemistryCell BiologyMolecular Biology
2019English

The High Genetic Barrier of EFdA/MK-8591 Stems From Strong Interactions With the Active Site of Drug-Resistant HIV-1 Reverse Transcriptase

Cell Chemical Biology
Molecular MedicineMolecular BiologyPharmacologyBiochemistryClinical BiochemistryDrug Discovery
2018English

Analysis of Mutations at Positions 115 and 116 in the dNTP Binding Site of HIV-1 Reverse Transcriptase

Proceedings of the National Academy of Sciences of the United States of America
Multidisciplinary
2000English

Inhibition of Reverse Transcriptase Activity Increases Stability of the HIV-1 Core

Journal of Virology
Insect ScienceImmunologyMicrobiologyVirology
2012English

Correction To: NMR Structure of the HIV-1 Reverse Transcriptase Thumb Subdomain

Journal of Biomolecular NMR
BiochemistrySpectroscopy
2017English

Biological Evaluation of Inhibitors of Reverse Transcriptase From HIV Type-1

Current Chemistry Letters
Chemistry
2015English

Anti-Hiv Drugs and Resistance: Inhibitors of HIV-1 Reverse Transcriptase and Protease

2012English

Amanote Research

Note-taking for researchers

Follow Amanote

© 2024 Amaplex Software S.P.R.L. All rights reserved.

Privacy PolicyRefund Policy