(PDF) The BCL-2 Protein Family, BH3-mimetics and Cancer

The BCL-2 Protein Family, BH3-mimetics and Cancer Therapy

Cell Death and Differentiation - United Kingdom

doi 10.1038/cdd.2015.50

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Abstract

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Date

May 8, 2015

Authors

A R D Delbridge

A Strasser

Publisher

Springer Science and Business Media LLC

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The BCL-2 Protein Family, BH3-mimetics and Cancer Therapy

Cell Death and Differentiation - United Kingdom

doi 10.1038/cdd.2015.50

Full Text

Abstract

Categories

Date

Authors

Publisher

Related search

Targeting the BCL-2 Family for Cancer Therapy

BH3 Mimetics: Their Action and Efficacy in Cancer Chemotherapy

Bfk: A Novel Weakly Proapoptotic Member of the BCL-2 Protein Family With a BH3 and a BH2 Region

Combining Bh3-Mimetics to Target Both BCL-2 and McL1 Has Potent Activity in Pre-Clinical Models of Acute Myeloid Leukemia

Multimodal Targeting of the BCL-2 Family in Cancer

BCL-xL-Inhibitory BH3 Mimetics (ABT-737 or ABT-263) and the Modulation of Cytosolic Calcium Flux and Platelet Function

The BCL-2 Homology Domain 3 (BH3)-only Proteins Bim and Bid Are Functionally Active and Restrained by Anti-Apoptotic BCL-2 Family Proteins in Healthy Liver

Prognostic Impact of the Expression/Phosphorylation of the BH3-only Proteins of the BCL-2 Family in Glioblastoma Multiforme

High Expression of BCL-2 and BCL-Xl in Diffuse Large B-Cell Lymphoma Confer Poor Prognosis but May Be Reversible by Combined Inhibition With Bet Inhibitors and Bh3 Mimetics.