Direct Inhibition of Oncogenic KRAS by Hydrocarbon-Stapled SOS1 Helices

Proceedings of the National Academy of Sciences of the United States of America - United States
doi 10.1073/pnas.1413185112
Full Text
Abstract

Available in full text

Date
Authors
Publisher

Proceedings of the National Academy of Sciences

Related search

Biophysical Determinants for Cellular Uptake of Hydrocarbon-Stapled Peptide Helices

Nature Chemical Biology
Cell BiologyMolecular Biology
2016English

KRAS G12C NSCLC Models Are Sensitive to Direct Targeting of KRAS in Combination With PI3K Inhibition.

Clinical Cancer Research
Cancer ResearchOncology
2018English

Correction: Colorectal Tumors Are Effectively Eradicated by Combined Inhibition of -Catenin, KRAS, and the Oncogenic Transcription Factor ITF2

Cancer Research
Cancer ResearchOncology
2010English

A KRAS-NRF2-53BP1 Nonhomologous End-Joining Repair Pathway Mediates Oncogenic KRAS Radioresistance

International Journal of Radiation Oncology Biology Physics
OncologyRadiologyCancer ResearchRadiationNuclear MedicineImaging
2017English

Oncogenic KRAS Drives Immune Suppression in Colorectal Cancer

Cancer Cell
Cancer ResearchOncologyCell Biology
2019English

Selective Targeting of KRAS Oncogenic Alleles by CRISPR/Cas9 Inhibits Proliferation of Cancer Cells

Scientific Reports
Multidisciplinary
2018English

SREBP1 Regulates Mitochondrial Metabolism in Oncogenic KRAS Expressing NSCLC

2020English

Targeting Oncogenic Protein Kinase Cι for Treatment of Mutant KRAS LADC

Small GTPases
BiochemistryCell Biology
2016English

KRAS Insertion Mutations Are Oncogenic and Exhibit Distinct Functional Properties

Nature Communications
AstronomyGeneticsMolecular BiologyBiochemistryChemistryPhysics
2016English

Amanote Research

Note-taking for researchers

Follow Amanote

© 2024 Amaplex Software S.P.R.L. All rights reserved.

Privacy PolicyRefund Policy