HER2 Overexpression Renders Human Breast Cancers Sensitive to PARP Inhibition Independently of Any Defect in Homologous Recombination DNA Repair

Cancer Research - United States
doi 10.1158/0008-5472.can-12-1287
Full Text
Abstract

Available in full text

Date
Authors
Publisher

American Association for Cancer Research (AACR)

Related search

SAMHD1 Promotes DNA End Resection to Facilitate DNA Repair by Homologous Recombination

Cell Reports
BiochemistryGeneticsMolecular Biology
2017English

The Deubiquitylating Enzyme USP15 Regulates Homologous Recombination Repair and Cancer Cell Response to PARP Inhibitors

Nature Communications
AstronomyGeneticsMolecular BiologyBiochemistryChemistryPhysics
2019English

Loss of NFBD1/MDC1 Disrupts Homologous Recombination Repair and Sensitizes Nasopharyngeal Carcinoma Cells to PARP Inhibitors

Journal of Biomedical Science
Cell BiologyPharmacologyBiochemistryEndocrinologyClinical BiochemistryMolecular BiologyMedicineMetabolismDiabetes
2019English

P16INK4a Impairs Homologous Recombination–Mediated DNA Repair in Human Papillomavirus–Positive Head and Neck Tumors

Cancer Research
Cancer ResearchOncology
2014English

mTOR Inhibitors Suppress Homologous Recombination Repair and Synergize With PARP Inhibitors via Regulating SUV39H1 in BRCA-Proficient Triple-Negative Breast Cancer

Clinical Cancer Research
Cancer ResearchOncology
2015English

PARP-1 Ensures Regulation of Replication Fork Progression by Homologous Recombination on Damaged DNA

Journal of Cell Biology
MedicineCell Biology
2008English

Reconstituted System for the Examination of Repair DNA Synthesis in Homologous Recombination

DNA Repair Enzymes: Cell, Molecular, and Chemical Biology
2017English

Inhibition of mTOR Downregulates Expression of DNA Repair Proteins and Is Highly Efficient Against BRCA2-mutated Breast Cancer in Combination to PARP Inhibition

Oncotarget
Oncology
2018English

The Role of the Human SWI5-MEI5 Complex in Homologous Recombination Repair

Journal of Biological Chemistry
BiochemistryCell BiologyMolecular Biology
2011English

Amanote Research

Note-taking for researchers

Follow Amanote

© 2024 Amaplex Software S.P.R.L. All rights reserved.

Privacy PolicyRefund Policy