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Multiparameter Lead Optimization to Give an Oral Checkpoint Kinase 1 (CHK1) Inhibitor Clinical Candidate: (R)5-((4-((Morpholin-2-Ylmethyl)amino)-5-(Trifluoromethyl)pyridin-2-Yl)amino)pyrazine-2-Carbonitrile (CCT245737)
doi 10.1021/acs.jmedchem.5b01938.s002
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American Chemical Society (ACS)
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