Targeting the TGFβ Pathway With Galunisertib, a TGFβRI SMI, Promotes Anti-Tumor Immunity Leading to Durable, Complete Responses, as Monotherapy and in Combination With Checkpoint Inhibition

Journal for ImmunoTherapy of Cancer - United Kingdom
doi 10.1186/2051-1426-3-s2-p402
Full Text
Abstract

Available in full text

Date
Authors
Publisher

BMJ

Related search

Anti-Nkg2a mAb Is a Checkpoint Inhibitor That Promotes Anti-Tumor Immunity by Unleashing Both T and NK Cells

Cell
BiochemistryGeneticsMolecular Biology
2018English

Combining Anti-Ctla4 With RG7787, an Immunotoxin Targeting Mesothelin, Promotes Tumor Eradication

Journal for ImmunoTherapy of Cancer
OncologyMolecular MedicinePharmacologyCancer ResearchAllergyImmunology
2015English

Targeting NKT Cells and PD-L1 Pathway Results in Augmented Anti-Tumor Responses in a Melanoma Model

Cancer Immunology, Immunotherapy
Cancer ResearchMedicineOncologyAllergyImmunology
2011English

Chemoradiation Combined With Phosphatidylserine-Targeting Antibody Enhances Systemic Anti-Tumor Immune Responses

International Journal of Radiation Oncology Biology Physics
OncologyRadiologyCancer ResearchRadiationNuclear MedicineImaging
2017English

Schweinfurthin Natural Products Induce Regression of Murine Melanoma and Pair With Anti-Pd-1 Therapy to Facilitate Durable Tumor Immunity

OncoImmunology
OncologyAllergyImmunology
2018English

Targeting PIM Kinase With PD1 Inhibition Improves Immunotherapeutic Anti-Tumor T Cell Response

Clinical Cancer Research
Cancer ResearchOncology
2019English

Copanlisib in Combination With Anti-Pd-1 Induces Regression in Animal Tumor Models Insensitive or Resistant to the Monotherapies of Pi3k and Checkpoint Inhibitors

Hematological Oncology
MedicineCancer ResearchOncologyHematology
2017English

Inhibition of Ataxia-Telangiectasia Mutated and RAD3-related (ATR) Overcomes Oxaliplatin Resistance and Promotes Anti-Tumor Immunity in Colorectal Cancer.

Cancer Research
Cancer ResearchOncology
2019English

TGFβ Blockade Enhances Radiotherapy Abscopal Efficacy Effects in Combination With Anti-Pd1 and Anti-Cd137 Immunostimulatory Monoclonal Antibodies

Molecular Cancer Therapeutics
Cancer ResearchOncology
2019English

Amanote Research

Note-taking for researchers

Follow Amanote

© 2024 Amaplex Software S.P.R.L. All rights reserved.

Privacy PolicyRefund Policy