Potential Neuroprotective Drug Evp4593 Reduces Excessive Expression of Huntingtin in iPSC-Based Juvenile Model of Huntington's Disease

Biophysical Journal - United States
doi 10.1016/j.bpj.2018.11.1311
Full Text
Abstract

Available in full text

Categories
Biophysics
Date
Authors
Publisher

Elsevier BV

Related search

Neuronal Targets for Reducing Mutant Huntingtin Expression to Ameliorate Disease in a Mouse Model of Huntington's Disease

Nature Medicine
BiochemistryMedicineGeneticsMolecular Biology
2014English

Sustained Therapeutic Reversal of Huntington's Disease by Transient Repression of Huntingtin Synthesis

Neuron
Neuroscience
2012English

“Huntingtin Holiday”: Progress Toward an Antisense Therapy for Huntington's Disease

Neuron
Neuroscience
2012English

Characterization of Human iPSC-derived Astrocytes With Potential for Disease Modeling and Drug Discovery

2019English

Factors Modulating the Interaction of Huntingtin With Lipid Membranes: Implications for Huntington's Disease

Biophysical Journal
Biophysics
2016English

‘Tissue’ Transglutaminase Ablation Reduces Neuronal Death and Prolongs Survival in a Mouse Model of Huntington's Disease

Cell Death and Differentiation
Cell BiologyMolecular Biology
2002English

Ubiquilin-1 Overexpression Increases the Lifespan and Delays Accumulation of Huntingtin Aggregates in the R6/2 Mouse Model of Huntington's Disease

PLoS ONE
Multidisciplinary
2014English

Biophysical Insights Into How Lipid Membranes Modulate Huntingtin Aggregation Associated With Huntington's Disease

Biophysical Journal
Biophysics
2019English

Drug Repurposing for Alzheimer’s Disease Based on Transcriptional Profiling of Human iPSC-derived Cortical Neurons

Translational Psychiatry
PsychiatryMolecular NeuroscienceBiological PsychiatryMental HealthCellular
2019English

Amanote Research

Note-taking for researchers

Follow Amanote

© 2024 Amaplex Software S.P.R.L. All rights reserved.

Privacy PolicyRefund Policy