A Structurally Altered Human Reduced Folate Carrier With Increased Folic Acid Transport Mediates a Novel Mechanism of Antifolate Resistance

Journal of Biological Chemistry - United States
doi 10.1074/jbc.273.46.30189
Full Text
Abstract

Available in full text

Date
Authors
Publisher

American Society for Biochemistry & Molecular Biology (ASBMB)

Related search

Clustering of Mutations in the First Transmembrane Domain of the Human Reduced Folate Carrier in GW1843U89-resistant Leukemia Cells With Impaired Antifolate Transport and Augmented Folate Uptake

Journal of Biological Chemistry
BiochemistryCell BiologyMolecular Biology
2000English

Resistance to Multiple Novel Antifolates Is Mediated via Defective Drug Transport Resulting From Clustered Mutations in the Reduced Folate Carrier Gene in Human Leukaemia Cell Lines

Biochemical Journal
BiochemistryCell BiologyMolecular Biology
2002English

Folate-Mediated Targeted and Intracellular Delivery of Paclitaxel Using a Novel Deoxycholic Acid-O-Carboxymethylated Chitosan–folic Acid Micelles

International Journal of Nanomedicine
Organic ChemistryBiophysicsBiomaterialsPharmaceutical ScienceMedicineBioengineeringDrug DiscoveryNanoscienceNanotechnology
2012English

Mutations in the Reduced Folate Carrier Gene Which Confer Dominant Resistance to 5,10-Dideazatetrahydrofolate

Journal of Biological Chemistry
BiochemistryCell BiologyMolecular Biology
1998English

Isolation of Human cDNAs That Restore Methotrexate Sensitivity and Reduced Folate Carrier Activity in Methotrexate Transport-Defective Chinese Hamster Ovary Cells

Journal of Biological Chemistry
BiochemistryCell BiologyMolecular Biology
1995English

Xenopus Reduced Folate Carrier Regulates Neural Crest Development Epigenetically

PLoS ONE
Multidisciplinary
2011English

Atomic-Scale Synthesis of Nanoporous Gallium–zinc Oxynitride-Reduced Graphene Oxide Photocatalyst With Tailored Carrier Transport Mechanism

RSC Advances
ChemistryChemical Engineering
2020English

High Dietary Folic Acid and High Plasma Folate in Children and Adults With Phenylketonuria

JIMD Reports
Internal MedicineGeneticsMolecular BiologyBiochemistryEndocrinologyMetabolismDiabetes
2013English

Reduced Expression of P27 Is a Novel Mechanism of Docetaxel Resistance in Breast Cancer Cells

Breast Cancer Research
Cancer ResearchOncology
2004English

Amanote Research

Note-taking for researchers

Follow Amanote

© 2024 Amaplex Software S.P.R.L. All rights reserved.

Privacy PolicyRefund Policy