Molecular Basis for the Loss-Of-Function Effects of the Alzheimer’s Disease–associated R47H Variant of the Immune Receptor TREM2

Journal of Biological Chemistry - United States
doi 10.1074/jbc.ra118.002352
Full Text
Abstract

Available in full text

Date
Authors
Publisher

American Society for Biochemistry & Molecular Biology (ASBMB)

Related search

Evidence of Trem2 Variant Associated With Triple Risk of Alzheimer’s Disease

PLoS ONE
Multidisciplinary
2014English

A Locked Immunometabolic Switch Underlies TREM2 R47H Loss of Function in Human iPSC--derived Microglia

2019English

New Insights Into the Role of TREM2 in Alzheimer’s Disease

Molecular Neurodegeneration
Molecular NeuroscienceNeurologyMolecular BiologyCellular
2018English

Unravelling the Molecular Basis for Regulatory T-Cell Plasticity and Loss of Function in Disease

Clinical and Translational Immunology
AllergyImmunologyNursing
2018English

The Human Glucocorticoid Receptor: Molecular Basis of Biologic Function

Steroids
Organic ChemistryMolecular BiologyPharmacologyBiochemistryEndocrinologyClinical Biochemistry
2010English

TREM2 Is Associated With Increased Risk for Alzheimer’s Disease in African Americans

Molecular Neurodegeneration
Molecular NeuroscienceNeurologyMolecular BiologyCellular
2015English

TREM2 Is Associated With the Risk of Alzheimer's Disease in Spanish Population

Neurobiology of Aging
AgingGerontologyDevelopmental BiologyGeriatricsNeuroscienceNeurology
2013English

Trinucleotide Repeats in the Human Androgen Receptor: A Molecular Basis for Disease

Journal of Molecular Endocrinology
EndocrinologyMolecular Biology
1998English

Molecular Basis of Dimethylglycine Dehydrogenase Deficiency Associated With Pathogenic Variant H109R

Journal of Inherited Metabolic Disease
Genetics
2008English

Amanote Research

Note-taking for researchers

Follow Amanote

© 2024 Amaplex Software S.P.R.L. All rights reserved.

Privacy PolicyRefund Policy