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Structure-Based Design and Synthesis of Macroheterocyclic Peptidomimetic Inhibitors of the Aspartic Protease B-Site Amyloid Precursor Protein Cleaving Enzyme (BACE)

doi 10.1021/jm060154a.s001

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Structure-Based Design and Synthesis of Macroheterocyclic Peptidomimetic Inhibitors of the Aspartic Protease B-Site Amyloid Precursor Protein Cleaving Enzyme (BACE)

doi 10.1021/jm060154a.s001

Full Text

Abstract

Date

Authors

Publisher

Related search

Design, Synthesis, and Crystal Structure of Hydroxyethyl Secondary Amine-Based Peptidomimetic Inhibitors of Human B-Secretase

Interaction of the Cytosolic Domains of sorLA/LR11 With the Amyloid Precursor Protein (APP) and Beta-Secretase Beta-Site APP-Cleaving Enzyme

Inhibition of Β-Site Amyloid Precursor Protein Cleaving Enzyme 1 and Cholinesterases by Pterosins via a Specific Structure−activity Relationship With a Strong BBB Permeability

Destruxin E Decreases Beta-Amyloid Generation by Reducing Colocalization of Beta-Amyloid-Cleaving Enzyme 1 and Beta-Amyloid Protein Precursor

Β-Site APP-cleaving Enzyme 1 (BACE1); Β-Amyloid (Aβ)

Alternative Selection of Β-Site APP-Cleaving Enzyme 1 (BACE1) Cleavage Sites in Amyloid Β-Protein Precursor (APP) Harboring Protective and Pathogenic Mutations Within the Aβ Sequence

Importance of the Caspase Cleavage Site in Amyloid-Β Protein Precursor

Distribution of a Human Brain Carboxypeptidase B Capable of Cleaving .BETA.-Amyloid Precursor Protein (APP) in Normal and Aizheimer's Diseased Brain.

Structure-Based Design, Synthesis, and Biological Evaluation of Non-Acyl Sulfamate Inhibitors of the Adenylate-Forming Enzyme MenE