The Brain-Penetrant Clinical ATM Inhibitor AZD1390 Radiosensitizes and Improves Survival of Preclinical Brain Tumor Models

Science advances - United States
doi 10.1126/sciadv.aat1719
Full Text
Abstract

Available in full text

Date
Authors
Publisher

American Association for the Advancement of Science (AAAS)

Related search

A Brain Penetrant Mutant IDH1 Inhibitor Provides in Vivo Survival Benefit

Scientific Reports
Multidisciplinary
2017English

Identification of a Potent, Highly Selective, and Brain Penetrant Phosphodiesterase 2A Inhibitor Clinical Candidate

English

Discovery of Clinical Development Candidate GDC-0084, a Brain Penetrant Inhibitor of PI3K and mTOR

English

A Brain-Penetrant MET Inhibitor Achieves Responses in Glioblastoma

Cancer Discovery
Oncology
2018English

Elucidating the Severity of Preclinical Traumatic Brain Injury Models

Clinical Neurosurgery
SurgeryNeurology
2014English

Atm Deletion With Dual Recombinase Technology Preferentially Radiosensitizes Tumor Endothelium

Journal of Clinical Investigation
Medicine
2014English

Cannabinoids in Neurodegenerative Disorders and Stroke/Brain Trauma: From Preclinical Models to Clinical Applications

Neurotherapeutics
NeurologyPharmacology
2015English

Fatal Measles Virus Infection Prevented by Brain-Penetrant Fusion Inhibitors

Journal of Virology
Insect ScienceImmunologyMicrobiologyVirology
2013English

Adjuvant Stereotactic Radiosurgery to the Tumor Bed Improves Local Control and Progression Free Survival Following Gross Total Resection of Brain Metastases

International Journal of Radiation Oncology Biology Physics
OncologyRadiologyCancer ResearchRadiationNuclear MedicineImaging
2015English

Amanote Research

Note-taking for researchers

Follow Amanote

© 2024 Amaplex Software S.P.R.L. All rights reserved.

Privacy PolicyRefund Policy