Discovery and Development of 5-[(5s, 9r)-9-(4-Cyanophenyl)-3-(3, 5-Dichlorophenyl)-1-Methyl-2, 4-Dioxo-1, 3, 7-Triazaspiro[4.4]non-7-Yl-Methyl]-3-Thiophenecarboxylicacid (BMS-587101)sA Small Molecule Antagonist Leukocyte Function Associated Antigen-1