Therapeutic Targeting of Tumor-Derived R-Spondin Attenuates -Catenin Signaling and Tumorigenesis in Multiple Cancer Types

Cancer Research - United States
doi 10.1158/0008-5472.can-15-0561
Full Text
Abstract

Available in full text

Date
Authors
Publisher

American Association for Cancer Research (AACR)

Related search

R-Spondin Potentiates WNT/Β-Catenin Signaling Through Orphan Receptors LGR4 and LGR5

PLoS ONE
Multidisciplinary
2012English

Targeting the WNT Signaling Pathway Through R-Spondin 3 Identifies an Anti-Fibrosis Treatment Strategy for Multiple Organs

PLoS ONE
Multidisciplinary
2020English

Protein Kinase D1 Attenuates Tumorigenesis in Colon Cancer by Modulating Β-Catenin/T Cell Factor Activity

Oncotarget
Oncology
2014English

Mianserin Suppresses R-Spondin 2-Induced Activation of WNT/Β-Catenin Signaling in Chondrocytes and Prevents Cartilage Degradation in a Rat Model of Osteoarthritis

Scientific Reports
Multidisciplinary
2019English

R-Spondin Homolog (RSPO1)

Science-Business eXchange
2011English

miR-663 Attenuates Tumor Growth and Invasiveness by Targeting eEF1A2 in Pancreatic Cancer

Molecular Cancer
Cancer ResearchOncologyMolecular Medicine
2015English

LGR4 and LGR5 Are R-Spondin Receptors Mediating WNT/Β-Catenin and WNT/PCP Signalling

EMBO Reports
BiochemistryGeneticsMolecular Biology
2011English

SOX15 and Other SOX Family Members Are Important Mediators of Tumorigenesis in Multiple Cancer Types.

Oncoscience
Cancer ResearchOncology
2014English

Hippo Signaling Interactions With WNT/Β-Catenin and Notch Signaling Repress Liver Tumorigenesis

Journal of Clinical Investigation
Medicine
2016English

Amanote Research

Note-taking for researchers

Follow Amanote

© 2024 Amaplex Software S.P.R.L. All rights reserved.

Privacy PolicyRefund Policy