Blockade of Kv1.3 Potassium Channels Inhibits Differentiation and Granzyme B Secretion of Human CD8+ T Effector Memory Lymphocytes

PLoS ONE - United States
doi 10.1371/journal.pone.0054267
Full Text
Abstract

Available in full text

Date
Authors
Publisher

Public Library of Science (PLoS)

Related search

Augmentation of Effector CD8+ T Cell Generation With Enhanced Granzyme B Expression by IL-27

Journal of Immunology
AllergyImmunology
2005English

TIM-3 Engagement Promotes Effector Memory T Cell Differentiation of Human Antigen-Specific CD8 T Cells by Activating mTORC1

Journal of Immunology
AllergyImmunology
2017English

Voltage-Dependent Potassium Channels Kv1.3 and Kv1.5 in Human Cancer

Biophysical Journal
Biophysics
2012English

Regulation of Effector and Memory CD8 T Cell Differentiation by IL-2—A Balancing Act

Frontiers in Immunology
AllergyImmunology
2018English

Kv1.3 Channels Mark Functionally Competent CD8 + Tumor-Infiltrating Lymphocytes in Head and Neck Cancer

Cancer Research
Cancer ResearchOncology
2016English

Activated T-Cells Inhibit Neurogenesis by Releasing Granzyme B: Rescue by Kv1.3 Blockers

Journal of Neuroscience
Neuroscience
2010English

Kv1.3 Channel Blockade With the Vm24 Scorpion Toxin Attenuates the CD4+ Effector Memory T Cell Response to TCR Stimulation

Cell Communication and Signaling
BiochemistryCell BiologyMolecular Biology
2018English

Simultaneous Coexpression of Memory-Related and Effector-Related Genes by Individual Human CD8 T Cells Depends on Antigen Specificity and Differentiation

Journal of immunotherapy (Hagerstown, Md. : 1997)
Cancer ResearchAllergyImmunologyPharmacology
2012English

Polarized Granzyme Release Is Required for Antigen-Driven Transendothelial Migration of Human Effector Memory CD4 T Cells

Journal of Immunology
AllergyImmunology
2014English

Amanote Research

Note-taking for researchers

Follow Amanote

© 2024 Amaplex Software S.P.R.L. All rights reserved.

Privacy PolicyRefund Policy