Nrf2 Drives Oxidative Stress-Induced Autophagy in Nucleus Pulposus Cells via a Keap1/Nrf2/P62 Feedback Loop to Protect Intervertebral Disc From Degeneration

Cell Death and Disease - United Kingdom
doi 10.1038/s41419-019-1701-3
Full Text
Abstract

Available in full text

Date
Authors
Publisher

Springer Science and Business Media LLC

Related search

P62 Suppressed VK3-induced Oxidative Damage Through Keap1/Nrf2 Pathway in Human Ovarian Cancer Cells

Journal of Cancer
Oncology
2020English

Ligustrazine Prevents Intervertebral Disc Degeneration via Suppression of Aberrant TGFβ Activation in Nucleus Pulposus Cells

BioMed Research International
ImmunologyMolecular BiologyBiochemistryMicrobiology MedicineGenetics
2019English

P62-Keap1-Nrf2-Are Pathway: A Contentious Player for Selective Targeting of Autophagy, Oxidative Stress and Mitochondrial Dysfunction in Prion Diseases

Frontiers in Molecular Neuroscience
Molecular NeuroscienceMolecular BiologyCellular
2018English

The Role of Angiopoietin-2 in Nucleus Pulposus Cells During Human Intervertebral Disc Degeneration

Laboratory Investigation
Forensic MedicinePathologyCell BiologyMolecular Biology
2017English

In-Vivo Nucleus Pulposus-Specific Regulation of Adult Murine Intervertebral Disc Degeneration via WNT/Beta-Catenin Signaling

Scientific Reports
Multidisciplinary
2018English

Autophagy Inhibition Engages Nrf2-P62 Ub-Associated Signaling

Autophagy
Cell BiologyMolecular Biology
2011English

Human Bone Morphogenetic Protein 7 Transfected Nucleus Pulposus Cells Delay the Degeneration of Intervertebral Disc in Dogs

Journal of Orthopaedic Research
OrthopedicsSports Medicine
2017English

Β‑ecdysterone Protects Against Apoptosis by Promoting Autophagy in Nucleus Pulposus Cells and Ameliorates Disc Degeneration

Molecular Medicine Reports
OncologyGeneticsMolecular BiologyBiochemistryCancer ResearchMolecular Medicine
2019English

P62-Dependent Phase Separation of Patient-Derived KEAP1 Mutations and NRF2

Molecular and Cellular Biology
Cell BiologyMolecular Biology
2018English

Amanote Research

Note-taking for researchers

Follow Amanote

© 2024 Amaplex Software S.P.R.L. All rights reserved.

Privacy PolicyRefund Policy