Elaboration of a Fragment Library Hit Produces Potent and Selective Aspartate Semialdehyde Dehydrogenase Inhibitors

Bioorganic and Medicinal Chemistry - United Kingdom
doi 10.1016/j.bmc.2015.09.017
Full Text
Abstract

Available in full text

Date
Authors
Publisher

Elsevier BV

Related search

Molecular Docking and Enzymatic Evaluation to Identify Selective Inhibitors of Aspartate Semialdehyde Dehydrogenase

Bioorganic and Medicinal Chemistry
Organic ChemistryMolecular MedicineMolecular BiologyBiochemistryClinical BiochemistryPharmaceutical ScienceDrug Discovery
2012English

Fragment-Based Discovery of Potent and Selective DDR1/2 Inhibitors

ACS Medicinal Chemistry Letters
Organic ChemistryBiochemistryDrug Discovery
2015English

Fragment-Based Discovery of Potent and Selective DDR1/2 Inhibitors

2015English

Regulation of Aspartokinase, Aspartate Semialdehyde Dehydrogenase, Dihydrodipicolinate Synthase and Dihydrodipicolinate Reductase in Lactobacillus Plantarum

Microbiology
Microbiology
2006English

Identifying Potent, Selective Protein Tyrosine Phosphatase Inhibitors From a Library of Au(I) Complexes

Journal of Medicinal Chemistry
Drug DiscoveryMolecular Medicine
2009English

Mammalian Methylmalonate-Semialdehyde Dehydrogenase

Methods in Enzymology
2000English

Identification of Highly Selective and Potent Histone Deacetylase 3 Inhibitors Using Click Chemistry-Based Combinatorial Fragment Assembly

PLoS ONE
Multidisciplinary
2013English

Triazolopyrimidine-Based Dihydroorotate Dehydrogenase Inhibitors With Potent and Selective Activity Against the Malaria ParasitePlasmodium Falciparum

Journal of Medicinal Chemistry
Drug DiscoveryMolecular Medicine
2008English

A Novel Α-Ketoglutaric Semialdehyde Dehydrogenase

Journal of Biological Chemistry
BiochemistryCell BiologyMolecular Biology
2006English

Amanote Research

Note-taking for researchers

Follow Amanote

© 2024 Amaplex Software S.P.R.L. All rights reserved.

Privacy PolicyRefund Policy