In Vivo and in Vitro Characterization of a First-In-Class Novel Azole Analog That Targets Pregnane X Receptor Activation

Molecular Pharmacology - United States
doi 10.1124/mol.111.071787
Full Text
Abstract

Available in full text

Date
Authors
Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Related search

Ligand-Dependent Activation of Transcription in Vitro by Retinoic Acid Receptor /Retinoid X Receptor Heterodimers That Mimics Transactivation by Retinoids in Vivo

Proceedings of the National Academy of Sciences of the United States of America
Multidisciplinary
1999English

Sulforaphane Is Not an Effective Antagonist of the Human Pregnane X-Receptor in Vivo

Toxicology and Applied Pharmacology
ToxicologyPharmacology
2013English

Novel Receptor Targets for Production and Action of Allopregnanolone in the Central Nervous System: A Focus on Pregnane Xenobiotic Receptor

Frontiers in Cellular Neuroscience
Molecular NeuroscienceCellular
2014English

Pregnane X Receptor (PXR) Activation: A Mechanism for Neuroprotection in a Mouse Model of Niemann-Pick C Disease

Proceedings of the National Academy of Sciences of the United States of America
Multidisciplinary
2006English

AZD3514: A Small Molecule That Modulates Androgen Receptor Signaling and Function in Vitro and in Vivo

Molecular Cancer Therapeutics
Cancer ResearchOncology
2013English

A Novel Small Inhibitor, LLL12, Targets STAT3 in Non‑small Cell Lung Cancer In�vitro and In�vivo

Oncology Letters
Cancer ResearchOncology
2018English

Complementary Roles of Farnesoid X Receptor, Pregnane X Receptor, and Constitutive Androstane Receptor in Protection Against Bile Acid Toxicity

Journal of Biological Chemistry
BiochemistryCell BiologyMolecular Biology
2003English

In Vitro and in Silico Characterization of Lemborexant (E2006), a Novel Dual Orexin Receptor Antagonist

Journal of Pharmacology and Experimental Therapeutics
Molecular MedicinePharmacology
2017English

In Vivo and in Vitro Characterization of a Novel MAO-B Inhibitor Radioligand, 18f-Labeled Deuterated Fluorodeprenyl

Journal of Nuclear Medicine
MedicineNuclear MedicineRadiologyImaging
2015English

Amanote Research

Note-taking for researchers

Follow Amanote

© 2025 Amaplex Software S.P.R.L. All rights reserved.

Privacy PolicyRefund Policy