The Impact of the Hepatocyte-To-Plasma pH Gradient on the Prediction of Hepatic Clearance and Drug-Drug Interactions for CYP2D6 Substrates

Drug Metabolism and Disposition - United States
doi 10.1124/dmd.116.071761
Full Text
Abstract

Available in full text

Date
Authors
Publisher

American Society for Pharmacology & Experimental Therapeutics (ASPET)

Related search

The Effect of CYP2D6 Drug-Drug Interactions on Hydrocodone Effectiveness

Academic Emergency Medicine
MedicineEmergency Medicine
2014English

Prediction of in Vivo Human Hepatic Clearance in Drug Discovery

Drug Metabolism and Pharmacokinetics
2000English

The Impact of Korean Prospective Drug Utilization Review Program on the Rate of Drug-Drug Interactions

Value in Health
MedicineHealth PolicyPublic HealthOccupational HealthEnvironmental
2013English

Physiologically Based Pharmacokinetic (Pbpk) Model of the Cyp2d6 Probe Atomoxetine: Extrapolation to Special Populations and Drug-Drug Interactions

Drug Metabolism and Disposition
PharmacologyPharmaceutical Science
2017English

The Impact of Formulation, Delivery, and Dosing Regimen on the Risk of Drug–Drug Interactions

Clinical Pharmacology and Therapeutics
Pharmacology
2019English

Modeling the Impact of Drug Interactions on Therapeutic Selectivity

Nature Communications
AstronomyGeneticsMolecular BiologyBiochemistryChemistryPhysics
2018English

A Novel Approach to the Prediction of Drug-Drug Interactions in Humans Based on the Serum Incubation Method

Drug Metabolism and Pharmacokinetics
PharmacologyPharmaceutical Science
2008English

Application of Physiologically Based Pharmacokinetic Modeling to the Understanding of Bosutinib Pharmacokinetics: Prediction of Drug–Drug and Drug–Disease Interactions

Drug Metabolism and Disposition
PharmacologyPharmaceutical Science
2017English

Manipulating In-House Designed Drug Databases for the Prediction of pH-Dependent Aqueous Drug Solubility

American Journal of Health Sciences (AJHS)
2013English

Amanote Research

Note-taking for researchers

Follow Amanote

© 2024 Amaplex Software S.P.R.L. All rights reserved.

Privacy PolicyRefund Policy