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Cover Feature: Highly Selective and Potent Human Β-Secretase 2 (BACE2) Inhibitors Against Type 2 Diabetes: Design, Synthesis, X-Ray Structure and Structure-Activity Relationship Studies (ChemMedChem 5/2019)

ChemMedChem - United Kingdom

doi 10.1002/cmdc.201900100

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Date

March 5, 2019

Authors

Bhavanam Sekhara Reddy

Kalapala Venketeswara Rao

Publisher

Wiley

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Cover Feature: Highly Selective and Potent Human Β-Secretase 2 (BACE2) Inhibitors Against Type 2 Diabetes: Design, Synthesis, X-Ray Structure and Structure-Activity Relationship Studies (ChemMedChem 5/2019)

ChemMedChem - United Kingdom

doi 10.1002/cmdc.201900100

Full Text

Abstract

Categories

Date

Authors

Publisher

Related search

Highly Selective and Potent Human Β-Secretase 2 (BACE2) Inhibitors Against Type 2 Diabetes: Design, Synthesis, X-Ray Structure and Structure-Activity Relationship Studies

Design, Synthesis and X-Ray Structure of Protein-Ligand Complexes: Important Insight Into Selectivity of Memapsin 2 (B-Secretase) Inhibitors

Cover Feature: Carboranyl Analogues of Celecoxib With Potent Cytostatic Activity Against Human Melanoma and Colon Cancer Cell Lines (ChemMedChem 3/2019)

Structure-Based Design of Potent and Selective CK1γ Inhibitors

Discovery of a New Class of Highly Potent Inhibitors of Acid Ceramidase: Synthesis and Structure–Activity Relationship (SAR)

Design, Synthesis and Structure-Activity Relationship of Functionalized Tetrahydro-Β-Carboline Derivatives as Novel PDE5 Inhibitors

Front Cover: Structure–Activity and Structure–Toxicity Relationships of Peptoid‐Based Histone Deacetylase Inhibitors With Dual‐Stage Antiplasmodial Activity (ChemMedChem 9/2019)

Cover Feature: 2‐Phenyloxazole‐4‐carboxamide as a Scaffold for Selective Inhibition of Human Monoamine Oxidase B (ChemMedChem 18/2019)

Identification of Potent Inhibitors for Β-Secretase Through Structure Based Virtual Screening and Molecular Dynamics Simulations