Epidermal Growth Factor Receptors With Tyrosine Kinase Domain Mutations Exhibit Reduced CBL Association, Poor Ubiquitylation, and Down-Regulation but Are Efficiently Internalized

Cancer Research - United States
doi 10.1158/0008-5472.can-07-0484
Full Text
Abstract

Available in full text

Date
Authors
Publisher

American Association for Cancer Research (AACR)

Related search

Association With HSP90 Inhibits CBL-Mediated Down-Regulation of Mutant Epidermal Growth Factor Receptors

Cancer Research
Cancer ResearchOncology
2006English

Transcriptional Down-Regulation of Epidermal Growth Factor Receptors by Nerve Growth Factor Treatment of PC12 Cells

Journal of Biological Chemistry
BiochemistryCell BiologyMolecular Biology
1998English

Negative Regulation of Receptor Tyrosine Kinases: Unexpected Links to C-CBL and Receptor Ubiquitylation

Cell Research
Cell BiologyMolecular Biology
2005English

Early Radiographic Response to Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitor in Non-Small Cell Lung Cancer Patients With Epidermal Growth Factor Receptor Mutations: A Prospective Study

Biomedical Journal
Medicine
2015English

Pertuzumab Increases Epidermal Growth Factor Receptor Down-Regulation by Counteracting Epidermal Growth Factor Receptor-ErbB2 Heterodimerization

Molecular Cancer Therapeutics
Cancer ResearchOncology
2009English

Interaction of Phosphatidylinositol 3-Kinase-Associated P85 With Epidermal Growth Factor and Platelet-Derived Growth Factor Receptors.

Molecular and Cellular Biology
Cell BiologyMolecular Biology
1992English

How Sensitive Are Epidermal Growth Factor Receptor–Tyrosine Kinase Inhibitors for Squamous Cell Carcinoma of the Lung Harboring EGFR Gene–Sensitive Mutations?

Journal of Thoracic Oncology
MedicineOncologyRespiratory MedicinePulmonary
2014English

Nucleotide Binding by the Epidermal Growth Factor Receptor Protein-Tyrosine Kinase

Journal of Biological Chemistry
BiochemistryCell BiologyMolecular Biology
1996English

Epidermal Growth Factor (EGF) Activates Nuclear Factor-κB Through IκBα Kinase-Independent but EGF Receptor-Kinase Dependent Tyrosine 42 Phosphorylation of IκBα

Oncogene
Cancer ResearchGeneticsMolecular Biology
2007English

Amanote Research

Note-taking for researchers

Follow Amanote

© 2024 Amaplex Software S.P.R.L. All rights reserved.

Privacy PolicyRefund Policy