PBPK Models for CYP3A4 and P-Gp DDI Prediction: A Modeling Network of Rifampicin, Itraconazole, Clarithromycin, Midazolam, Alfentanil and Digoxin

CPT: Pharmacometrics and Systems Pharmacology - United States
doi 10.1002/psp4.12343
Full Text
Abstract

Available in full text

Date
Authors
Publisher

Wiley

Related search

The IC50 for Inhibition of Digoxin Transport Across Confluent Cell Monolayers of P-Gp Expressing Cell Lines Is Often a Function of Inhibitor Binding to Both P-Gp and an Unidentified Basolateral Digoxin Uptake Transporter

Biophysical Journal
Biophysics
2013English

Sedation for Upper Gastrointestinal Endoscopy: A Comparison of Alfentanil-Midazolam and Meperidine-Diazepam

Canadian Journal of Anaesthesia
MedicineAnesthesiologyPain Medicine
1994English

Frog Intestinal Perfusion to Evaluate Drug Permeability: Application to P-Gp and Cyp3a4 Substrates

Frontiers in Pharmacology
Pharmacology
2015English

The Effect of Itraconazole and Rifampicin on the Pharmacokinetics of Osimertinib

British Journal of Clinical Pharmacology
Pharmacology
2018English

Transport Inhibition of Digoxin Using Several Common P-Gp Expressing Cell Lines Is Not Necessarily Reporting Only on Inhibitor Binding to P-Gp

PLoS ONE
Multidisciplinary
2013English

P-Gp and Taxanes

Oncoscience
Cancer ResearchOncology
2014English

Physiologically Based Pharmacokinetic (PBPK) Modeling Analysis for Quantitative Prediction of Renal Transporter-Mediated Interactions Between Metformin and Cimetidine

CPT: Pharmacometrics and Systems Pharmacology
ModelingSimulationCardiovascular MedicinePharmacologyCardiology
2019English

QSP and PBPK Modeling With Mrgsolve: A Hands‐on Tutorial

CPT: Pharmacometrics and Systems Pharmacology
ModelingSimulationCardiovascular MedicinePharmacologyCardiology
2019English

Prediction of Drug–Drug Interactions Between Opioids and Overdosed Benzodiazepines Using Physiologically Based Pharmacokinetic (PBPK) Modeling and Simulation

Drugs in R and D
Pharmacology
2019English

Amanote Research

Note-taking for researchers

Follow Amanote

© 2024 Amaplex Software S.P.R.L. All rights reserved.

Privacy PolicyRefund Policy