Up-Regulation of a Thermogenesis-Related Gene (UCP1) and Down-Regulation of PPARγ and aP2 Genes in Adipose Tissue: Possible Features of the Antiobesity Effects of a Β3-Adrenergic Agonist 1 1Abbreviations: AP2, Adipocyte Specific Fatty Acid Binding Protein; BAT, Brown Adipose Tissue; DIO, Diet-Induced Obesity; HFD, High-Fat Diet; PPARγ, Peroxisome Proliferator-Activated Receptor Gamma; RXRα, Retinoid X Receptor Alpha; RARα, Retinoid Acid Receptor Alpha; UCP, Uncoupling Protein; WAT, White Adipose Tissue; RT-PCR, Reverse Transcription-Polymerase Chain Reaction; M-Mlv, Moloney-Murine Leukemia Virus.
Biochemical Pharmacology - Netherlands
doi 10.1016/s0006-2952(01)00562-7
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June 1, 2001
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Elsevier BV