An Epigenetic Pathway Regulates Sensitivity of Breast Cancer Cells to HER2 Inhibition via FOXO/c-Myc Axis

Cancer Cell- United States

doi 10.1016/j.ccell.2015.09.005

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October 1, 2015

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Elsevier BV

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An Epigenetic Pathway Regulates Sensitivity of Breast Cancer Cells to HER2 Inhibition via FOXO/c-Myc Axis

Cancer Cell- United States

Full Text

Abstract

Categories

Date

Authors

Publisher

Related search

Danazol Mediates Collateral Sensitivity via STAT3/Myc Related Pathway in Multidrug-Resistant Cancer Cells

Pharmacologic Inhibition of mTOR Improves Lapatinib Sensitivity in HER2-Overexpressing Breast Cancer Cells With Primary Trastuzumab Resistance

NRF2 Regulates HER2 and HER3 Signaling Pathway to Modulate Sensitivity to Targeted Immunotherapies

De-Repression of the P21 Promoter in Prostate Cancer Cells by an Isothiocyanate via Inhibition of HDACs and C-Myc

Breast Cancer Stem Cells in HER2-negative Breast Cancer Cells Contribute to HER2-mediated Radioresistance and Molecular Subtype Conversion: Clinical Implications for Serum HER2 in Recurrent HER2-negative Breast Cancer

PIN1 Maintains Redox Balance via the C-Myc/Nrf2 Axis to Counteract Kras-Induced Mitochondrial Respiratory Injury in Pancreatic Cancer Cells.

Targeting HER2+ Breast Cancer: The TBK1/IKK-Epsilon Axis

JQ1, an Inhibitor of the Epigenetic Reader BRD4, Suppresses the Bidirectional MYC-AP4 Axis via Multiple Mechanisms

Pharmacological Targeting of MYC-regulated IRE1/XBP1 Pathway Suppresses MYC-driven Breast Cancer