Chemical Lead Optimization of a Pan Gq mAChR M1, M3, M5 Positive Allosteric Modulator (PAM) Lead. Part I: Development of the First Highly Selective M5 PAM

Bioorganic and Medicinal Chemistry Letters - United Kingdom
doi 10.1016/j.bmcl.2009.11.089
Full Text
Abstract

Available in full text

Date
Authors
Publisher

Elsevier BV

Related search

Molecular Basis of Action of a Small Molecule Positive Allosteric Modulator (PAM)-agonist at the Type 1 Cholecystokinin Holoreceptor

Molecular Pharmacology
Molecular MedicinePharmacology
2018English

Heterobiaryl and Heterobiaryl Ether Derived M5 Positive Allosteric Modulators

Bioorganic and Medicinal Chemistry Letters
Organic ChemistryMolecular MedicineMolecular BiologyBiochemistryClinical BiochemistryPharmaceutical ScienceDrug Discovery
2010English

Further Optimization of the M5 NAM MLPCN Probe ML375: Tactics and Challenges

Bioorganic and Medicinal Chemistry Letters
Organic ChemistryMolecular MedicineMolecular BiologyBiochemistryClinical BiochemistryPharmaceutical ScienceDrug Discovery
2015English

Population Pharmacokinetics of Micafungin and Its Metabolites M1 and M5 in Children and Adolescents

Antimicrobial Agents and Chemotherapy
Infectious DiseasesPharmacology
2014English

Intersecting M2- And M5-Branes

Physics Letters, Section B: Nuclear, Elementary Particle and High-Energy Physics
High Energy PhysicsNuclear
2004English

Low-Power DAC-less PAM-4 Transmitter Using a Cascaded Microring Modulator

Optics Letters
OpticsAtomicMolecular Physics,
2016English

Positive Allosteric Modulators of the Metabotropic Glutamate Receptor Subtype 4 (mGluR4). Part II: Challenges in Hit-To-Lead

Bioorganic and Medicinal Chemistry Letters
Organic ChemistryMolecular MedicineMolecular BiologyBiochemistryClinical BiochemistryPharmaceutical ScienceDrug Discovery
2009English

Towards 2+4 Formulation of M5-Brane

Journal of High Energy Physics
High Energy PhysicsNuclear
2015English

The M1 Muscarinic Positive Allosteric Modulator PQCA Improves Performance on Translatable Tests of Memory and Attention in Rhesus Monkeys

Journal of Pharmacology and Experimental Therapeutics
Molecular MedicinePharmacology
2015English

Amanote Research

Note-taking for researchers

Follow Amanote

© 2024 Amaplex Software S.P.R.L. All rights reserved.

Privacy PolicyRefund Policy