Hotspot Mutations in KIT Receptor Differentially Modulate Its Allosterically Coupled Conformational Dynamics: Impact on Activation and Drug Sensitivity

PLoS Computational Biology - United States
doi 10.1371/journal.pcbi.1003749
Full Text
Abstract

Available in full text

Date
Authors
Publisher

Public Library of Science (PLoS)

Related search

Retraction Note: Frequency of TP53 Mutations and Its Impact on Drug Sensitivity in Acute Myeloid Leukemia?

Indian Journal of Clinical Biochemistry
Clinical Biochemistry
2014English

Allosterically Targeting EGFR Drug-Resistance Gatekeeper Mutations

Journal of Thoracic Disease
PulmonaryRespiratory Medicine
2017English

Corrigendum: Ligand-Induced Conformational Changes Allosterically Activate Toll-Like Receptor 9

Nature Immunology
AllergyImmunology
2007English

Conformational Dynamics in the GABAA Receptor

Biophysical Journal
Biophysics
2015English

G-Protein-Coupled Receptor Dynamics: Dimerization and Activation Models Compared With Experiment

Biochemical Society Transactions
Biochemistry
2012English

Activating Mutations and Senescence Secretome: New Insights Into HER2 Activation, Drug Sensitivity and Metastatic Progression

Breast Cancer Research
Cancer ResearchOncology
2013English

The High- And Low-Affinity Receptor Binding Sites of Growth Hormone Are Allosterically Coupled

Proceedings of the National Academy of Sciences of the United States of America
Multidisciplinary
2004English

Lipids Modulate the Conformational Dynamics of a Secondary Multidrug Transporter

Nature Structural and Molecular Biology
Structural BiologyMolecular Biology
2016English

In Vivo Conformational Dynamics of Hsp90 and Its Interactors

Cell Chemical Biology
Molecular MedicineMolecular BiologyPharmacologyBiochemistryClinical BiochemistryDrug Discovery
2016English

Amanote Research

Note-taking for researchers

Follow Amanote

© 2024 Amaplex Software S.P.R.L. All rights reserved.

Privacy PolicyRefund Policy