Discriminating Agonist and Antagonist Ligands of the Nuclear Receptors Using 3d-Pharmacophores

Journal of Cheminformatics - United Kingdom
doi 10.1186/s13321-016-0154-2
Full Text
Abstract

Available in full text

Date
Authors
Publisher

Springer Science and Business Media LLC

Related search

Studies of the Prostanoid Receptors for Specific Agonist/Antagonist

Folia Pharmacologica Japonica
Pharmacology
2000English

Agonist Versus Antagonist Binding to Alpha-Adrenergic Receptors.

Proceedings of the National Academy of Sciences of the United States of America
Multidisciplinary
1980English

Development of CNS Multi-Receptor Ligands: Modification of Known D2 Pharmacophores

Bioorganic and Medicinal Chemistry
Organic ChemistryMolecular MedicineMolecular BiologyBiochemistryClinical BiochemistryPharmaceutical ScienceDrug Discovery
2016English

Synthesis and Characterization of 2-Substituted Bornane Pharmacophores for Novel Cannabinergic Ligands

Tetrahedron Letters
Organic ChemistryBiochemistryDrug Discovery
2008English

Discovery of Tripeptide-Derived Multifunctional Ligands Possessing Delta/Mu Opioid Receptor Agonist and Neurokinin 1 Receptor Antagonist Activities

Bioorganic and Medicinal Chemistry Letters
Organic ChemistryMolecular MedicineMolecular BiologyBiochemistryClinical BiochemistryPharmaceutical ScienceDrug Discovery
2015English

Truncation of the Peptide Sequence in Bifunctional Ligands With Mu and Delta Opioid Receptor Agonist and Neurokinin 1 Receptor Antagonist Activities

Bioorganic and Medicinal Chemistry Letters
Organic ChemistryMolecular MedicineMolecular BiologyBiochemistryClinical BiochemistryPharmaceutical ScienceDrug Discovery
2013English

Synthetic Route Towards Potential Bivalent Ligands Possessing Opioid and D2/D3 Pharmacophores

Journal of the Serbian Chemical Society
Chemistry
2019English

PROPERTIES OF THE TRPV4 AGONIST GSK1016790A AND the TRPV4 ANTAGONIST GSK2193874

Physiological Reviews
MedicinePhysiologyMolecular Biology
2017English

Estimation of the Receptor-State Affinity Constants of Ligands in Functional Studies Using Wild Type and Constitutively Active Mutant Receptors: Implications for Estimation of Agonist Bias

Journal of Pharmacological and Toxicological Methods
ToxicologyPharmacology
2017English

Amanote Research

Note-taking for researchers

Follow Amanote

© 2024 Amaplex Software S.P.R.L. All rights reserved.

Privacy PolicyRefund Policy