Molecular and Structural Basis for the Roles of Hepatitis C Virus Polymerase NS5B Amino Acids 15, 223, and 321 in Viral Replication and Drug Resistance

Antimicrobial Agents and Chemotherapy - United States
doi 10.1128/aac.03847-14
Full Text
Abstract

Available in full text

Date
Authors
Publisher

American Society for Microbiology

Related search

Binding Site Characterization and Resistance to a Class of Non-Nucleoside Inhibitors of the Hepatitis C Virus NS5B Polymerase

Journal of Biological Chemistry
BiochemistryCell BiologyMolecular Biology
2005English

A Cis-Acting Replication Element in the Sequence Encoding the NS5B RNA-Dependent RNA Polymerase Is Required for Hepatitis C Virus RNA Replication

Journal of Virology
Insect ScienceImmunologyMicrobiologyVirology
2004English

Prevalence of Amino Acid Mutations in Hepatitis C Virus Core and NS5B Regions Among Venezuelan Viral Isolates and Comparison With Worldwide Isolates

Virology Journal
VirologyInfectious Diseases
2012English

Molecular Modeling Study on the Drug Resistance Mechanism of NS5B Polymerase to TMC647055

Biochemistry and Cell Biology
BiochemistryCell BiologyMolecular Biology
2016English

Characterization of Thiobarbituric Acid Derivatives as Inhibitors of Hepatitis C Virus NS5B Polymerase

Virology Journal
VirologyInfectious Diseases
2011English

Inhibition of Hepatitis C Virus NS5B Polymerase by S-Trityl-L-Cysteine Derivatives

European Journal of Medicinal Chemistry
MedicineOrganic ChemistryDrug DiscoveryPharmacology
2012English

Hepatitis C Virus Non-Structural Proteins in the Probable Membranous Compartment Function in Viral Genome Replication

Journal of Biological Chemistry
BiochemistryCell BiologyMolecular Biology
2003English

Dynamics of Hepatitis C Virus (HCV) RNA-dependent RNA Polymerase NS5B in Complex With RNA

Journal of Biological Chemistry
BiochemistryCell BiologyMolecular Biology
2014English

Molecular and Contextual Markers of Hepatitis C Virus and Drug Abuse

Molecular Diagnosis and Therapy
MedicineMolecular MedicineGeneticsPharmacology
2009English

Amanote Research

Note-taking for researchers

Follow Amanote

© 2024 Amaplex Software S.P.R.L. All rights reserved.

Privacy PolicyRefund Policy