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Publications by A. DiFrancesco

Efficacy and Safety From a Phase 2B Trial of SM04690, a Novel, Intra-Articular, WNT Pathway Inhibitor for the Treatment of Osteoarthritis of the Knee

Osteoarthritis and Cartilage
Sports MedicineRheumatologyOrthopedicsBiomedical Engineering
2019English

A Novel WNT Pathway Inhibitor, SM04690, for the Treatment of Moderate to Severe Osteoarthritis of the Knee: Results of a 24-Week, Randomized, Controlled, Phase 1 Study

Osteoarthritis and Cartilage
Sports MedicineRheumatologyOrthopedicsBiomedical Engineering
2017English

Related publications

Comparison of Intra-Articular Sham and Vehicle Injection From a Phase 2b Trial of SM04690, a Small-Molecule WNT Inhibitor, for Knee Osteoarthritis

Osteoarthritis and Cartilage
Sports MedicineRheumatologyOrthopedicsBiomedical Engineering
2019English

OP0166 Radiographic Outcomes From a Randomized, Double-Blind, Placebo-Controlled, Phase 2 Study of a Novel, Intra-Articular, Injectable, WNT Pathway Inhibitor (SM04690) in the Treatment of Osteoarthritis of the Knee: Week 26 Interim Analysis

2017English

Discovery of a Small Molecule Inhibitor of the WNT Pathway (SM04690) as a Potential Disease Modifying Treatment for Knee Osteoarthritis

Osteoarthritis and Cartilage
Sports MedicineRheumatologyOrthopedicsBiomedical Engineering
2016English

Efficacy and Safety of Massage for Osteoarthritis of the Knee: A Randomized Clinical Trial

Journal of General Internal Medicine
Internal Medicine
2018English

Intra-Articular Injections for the Treatment of Osteoarthritis

Drugs in R and D
Pharmacology
2011English

SM04690, a Potential Disease-Modifying Treatment for Knee Osteoarthritis, Functions Through Inhibition of CLK2 and DYRK1A, Novel Molecular Regulators of WNT Signaling, Chondrogenesis, and Inflammation

Osteoarthritis and Cartilage
Sports MedicineRheumatologyOrthopedicsBiomedical Engineering
2019English

Safety, Tolerability and Efficacy of Intra-Articular Progenza in Knee Osteoarthritis: A Randomized Double-Blind Placebo-Controlled Single Ascending Dose Study

Journal of Translational Medicine
BiochemistryMedicineGeneticsMolecular Biology
2018English

Intra-Articular Hyaluronan Treatment of Patients With Knee Osteoarthritis Waiting for Replacement Surgery

The Open Arthritis Journal
2008English

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