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Publications by Alex H. M. Ng

Hul5 HECT Ubiquitin Ligase Plays a Major Role in the Ubiquitylation and Turnover of Cytosolic Misfolded Proteins

Nature Cell Biology

English

The Yeast Ubr1 Ubiquitin Ligase Participates in a Prominent Pathway That Targets Cytosolic Thermosensitive Mutants for Degradation

G3: Genes, Genomes, Genetics

Molecular Biology

English

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Functional Dissection of a HECT Ubiquitin E3 Ligase

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The HECT-type Ubiquitin Ligase Tom1 Contributes to the Turnover of Spo12, a Component of the FEAR Network, in G2/M Phase

Molecular Biology

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Analysis of the Role of Ubiquitin-Interacting Motifs in Ubiquitin Binding and Ubiquitylation

Journal of Biological Chemistry

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Crystal Structure of the Catalytic C‐lobe of the HECT‐type Ubiquitin Ligase E6AP

Protein Science

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A Human Ubiquitin Conjugating Enzyme (E2)-Hect E3 Ligase Structure-Function Screen

Molecular and Cellular Proteomics

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Molecular Determinants of Polyubiquitin Linkage Selection by an HECT Ubiquitin Ligase

Molecular Biology

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Targeting Hedgehog Signalling Through the Ubiquitylation Process: The Multiple Roles of the HECT-E3 Ligase Itch

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Selective Compounds Enhance Osteoblastic Activity by Targeting HECT Domain of Ubiquitin Ligase Smurf1

English

Ubiquitin Ligase Hul5 Is Required for Fragment-Specific Substrate Degradation in Endoplasmic Reticulum-Associated Degradation

Journal of Biological Chemistry

Molecular Biology

English