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Publications by Bruce J. Melancon

Allosteric Modulation of the M1 Muscarinic Acetylcholine Receptor: Improving Cognition and a Potential Treatment for Schizophrenia and Alzheimer's Disease

Drug Discovery Today
Drug DiscoveryPharmacology
2013English

Development of Novel M1 Antagonist Scaffolds Through the Continued Optimization of the MLPCN Probe ML012

Bioorganic and Medicinal Chemistry Letters
Organic ChemistryMolecular MedicineMolecular BiologyBiochemistryClinical BiochemistryPharmaceutical ScienceDrug Discovery
2012English

Discovery and Optimization of a Novel Series of Highly CNS Penetrant M 4 PAMs Based on a 5,6-Dimethyl-4-(Piperidin-1-Yl)thieno[2,3- D ]Pyrimidine Core

Bioorganic and Medicinal Chemistry Letters
Organic ChemistryMolecular MedicineMolecular BiologyBiochemistryClinical BiochemistryPharmaceutical ScienceDrug Discovery
2016English

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