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Publications by Bryan L. Roth

Structure-Based Discovery of Opioid Analgesics With Reduced Side Effects

Nature
Multidisciplinary
2016English

Activation Mechanisms for a Universal Signalling Protein

Nature
Multidisciplinary
2018English

Structural Basis for Smoothened Receptor Modulation and Chemoresistance to Anticancer Drugs

Nature Communications
AstronomyGeneticsMolecular BiologyBiochemistryChemistryPhysics
2014English

NMR Structure and Dynamics of the Agonist Dynorphin Peptide Bound to the Human Kappa Opioid Receptor

Proceedings of the National Academy of Sciences of the United States of America
Multidisciplinary
2015English

Chemogenetics—A Transformational and Translational Platform

JAMA Neurology
Neurology
2015English

4β-Methyl-5-(3-Hydroxyphenyl)morphan Opioid Agonist and Partial Agonist Derived From a 4β-Methyl-5-(3-Hydroxyphenyl)morphan Pure Antagonist

Journal of Medicinal Chemistry
Drug DiscoveryMolecular Medicine
2013English

Discovery of G Protein-Biased D2 Dopamine Receptor Partial Agonists

Journal of Medicinal Chemistry
Drug DiscoveryMolecular Medicine
2016English

Role of Kappa-Opioid Receptors in the Effects of Salvinorin a and Ketamine on Attention in Rats

Psychopharmacology
Pharmacology
2010English

Pharmacosynthetics: Reimagining the Pharmacogenetic Approach

Brain Research
NeuroscienceNeurologyDevelopmental BiologyMolecular Biology
2013English

Development of CNS Multi-Receptor Ligands: Modification of Known D2 Pharmacophores

Bioorganic and Medicinal Chemistry
Organic ChemistryMolecular MedicineMolecular BiologyBiochemistryClinical BiochemistryPharmaceutical ScienceDrug Discovery
2016English

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