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Publications by C. Barroga

Discovery of a Small Molecule Inhibitor of the WNT Pathway (SM04690) as a Potential Disease Modifying Treatment for Knee Osteoarthritis

Osteoarthritis and Cartilage
Sports MedicineRheumatologyOrthopedicsBiomedical Engineering
2016English

Related publications

Comparison of Intra-Articular Sham and Vehicle Injection From a Phase 2b Trial of SM04690, a Small-Molecule WNT Inhibitor, for Knee Osteoarthritis

Osteoarthritis and Cartilage
Sports MedicineRheumatologyOrthopedicsBiomedical Engineering
2019English

SM04690, a Potential Disease-Modifying Treatment for Knee Osteoarthritis, Functions Through Inhibition of CLK2 and DYRK1A, Novel Molecular Regulators of WNT Signaling, Chondrogenesis, and Inflammation

Osteoarthritis and Cartilage
Sports MedicineRheumatologyOrthopedicsBiomedical Engineering
2019English

Efficacy and Safety From a Phase 2B Trial of SM04690, a Novel, Intra-Articular, WNT Pathway Inhibitor for the Treatment of Osteoarthritis of the Knee

Osteoarthritis and Cartilage
Sports MedicineRheumatologyOrthopedicsBiomedical Engineering
2019English

A Novel WNT Pathway Inhibitor, SM04690, for the Treatment of Moderate to Severe Osteoarthritis of the Knee: Results of a 24-Week, Randomized, Controlled, Phase 1 Study

Osteoarthritis and Cartilage
Sports MedicineRheumatologyOrthopedicsBiomedical Engineering
2017English

OP0166 Radiographic Outcomes From a Randomized, Double-Blind, Placebo-Controlled, Phase 2 Study of a Novel, Intra-Articular, Injectable, WNT Pathway Inhibitor (SM04690) in the Treatment of Osteoarthritis of the Knee: Week 26 Interim Analysis

2017English

Arthroscopy as a Treatment for Knee Osteoarthritis

Best Practice and Research in Clinical Rheumatology
MedicineRheumatology
2010English

Discoidin Domain Receptor 2 as a Potential Therapeutic Target for Development of Disease-Modifying Osteoarthritis Drugs

American Journal of Pathology
Forensic MedicinePathology
2016English

Systems-Based Discovery of Tomatidine as a Natural Small Molecule Inhibitor of Skeletal Muscle Atrophy

Journal of Biological Chemistry
BiochemistryCell BiologyMolecular Biology
2014English

Discovery of SCY45, a Natural Small‐Molecule MDM2‐p53 Interaction Inhibitor.

Chemistry and Biodiversity
Molecular MedicineMolecular BiologyBiochemistryMedicineBioengineeringChemistry
2019English

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