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Publications by Charles W. Johannes
Stereoisomerism of Stapled Peptide Inhibitors of the P53-Mdm2 Interaction: An Assessment of Synthetic Strategies and Activity Profiles
Chemical Science
Chemistry
Macrocyclization of an All-D Linear Peptide Improves Target Affinity and Imparts Cellular Activity: A Novel Stapled Α-Helical Peptide Modality
Related publications
Synthesis of Cell-Permeable Stapled Peptide Dual Inhibitors of the P53-Mdm2/MDMX Interactions via Photoinduced Cycloaddition
Bioorganic and Medicinal Chemistry Letters
Organic Chemistry
Molecular Medicine
Molecular Biology
Biochemistry
Clinical Biochemistry
Pharmaceutical Science
Drug Discovery
A Dimethylbromobenzene-Cysteine Stapled Peptide Dual Inhibitor of the P53-Mdm2/MDMX Interactions
Hepatoma Research
Discovery of Potent and Simplified Piperidinone-Based Inhibitors of the MDM2–p53 Interaction
ACS Medicinal Chemistry Letters
Organic Chemistry
Biochemistry
Drug Discovery
P53 Mediated Death of Cells Overexpressing MDM2 by an Inhibitor of MDM2 Interaction With P53
Oncogene
Cancer Research
Genetics
Molecular Biology
A Stapled Peptide Antagonist of MDM2 Carried by Polymeric Micelles Sensitizes Glioblastoma to Temozolomide Treatment Through P53 Activation
Journal of Controlled Release
Pharmaceutical Science
Searching for Dual Inhibitors of the MDM2-p53 and MDMX-p53 Protein-Protein Interaction by a Scaffold-Hopping Approach
Chemical Biology and Drug Design
Biochemistry
Organic Chemistry
Drug Discovery
Molecular Medicine
Pharmacology
Structure of a Stapled Peptide Antagonist Bound to Nutlin-Resistant Mdm2
PLoS ONE
Multidisciplinary
Affinity-Based Screening of MDM2/MDMX–p53 Interaction Inhibitors by Chemical Array: Identification of Novel Peptidic Inhibitors
Bioorganic and Medicinal Chemistry Letters
Organic Chemistry
Molecular Medicine
Molecular Biology
Biochemistry
Clinical Biochemistry
Pharmaceutical Science
Drug Discovery
The Interaction Between P53 and Mdm2 Is Independent of MEG3–p53 Association
