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Publications by Chris J. Novotny
Procaspase-3 Activation as an Anti-Cancer Strategy: Structure−Activity Relationship of Procaspase-Activating Compound 1 (PAC-1) and Its Cellular Co-Localization With Caspase-3
Journal of Medicinal Chemistry
Drug Discovery
Molecular Medicine
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cIAP1 Cooperatively Inhibits Procaspase-3 Activation by the Caspase-9 Apoptosome
Journal of Biological Chemistry
Biochemistry
Cell Biology
Molecular Biology
Procaspase-3-Activating Compound 1 Stabilizes Hypoxia-Inducible Factor 1α and Induces DNA Damage by Sequestering Ferrous Iron
Cell Death and Disease
Molecular Neuroscience
Immunology
Cell Biology
Cancer Research
Cellular
Medicine
Caspase-2 Primes Cancer Cells for TRAIL-mediated Apoptosis by Processing Procaspase-8
EMBO Journal
Immunology
Molecular Biology
Biochemistry
Microbiology
Neuroscience
Medicine
Genetics
The Apaf-1•procaspase-9 Apoptosome Complex Functions as a Proteolytic-Based Molecular Timer
EMBO Journal
Immunology
Molecular Biology
Biochemistry
Microbiology
Neuroscience
Medicine
Genetics
Quantitative Structure Activity Relationship of 2, 5, 6–Trisubstituted Imidazo (2, 1-B)-1, 3, 4–Thiadiazole as Anticancer Compunds.
Indian Journal of Pharmaceutical Education and Research
Toxicology
Pharmaceutics
Pharmacology
Molecular Dynamics Simulation of the Conformational Changes in the Procaspase 9 Activation
Biophysical Journal
Biophysics
Survival of Motor Neuron Protein Over-Expression Prevents Calpain-Mediated Cleavage and Activation of Procaspase-3 in Differentiated Human SH-SY5Y Cells
Neuroscience
Neuroscience
Trichomonas Vaginalis Promotes Apoptosis of Human Neutrophils by Activating Caspase-3 and Reducing McL-1 Expression
Parasite Immunology
Parasitology
Immunology
Structure-Activity Relationship of 3- And 4-Acyloxy-1-(1,3-Dioxolan-4-Ylmethyl)piperidine Derivatives.
Chemical and Pharmaceutical Bulletin
Medicine
Drug Discovery
Chemistry