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Publications by Christian Haass

Secreted APP Modulates Synaptic Activity: A Novel Target for Therapeutic Intervention?

English

Early Lysosomal Maturation Deficits in Microglia Triggers Enhanced Lysosomal Activity in Other Brain Cells of Progranulin Knockout Mice

Molecular Neurodegeneration

Molecular Neuroscience

Molecular Biology

English

Increase of TREM2 During Aging of an Alzheimer’s Disease Mouse Model Is Paralleled by Microglial Activation and Amyloidosis

Frontiers in Aging Neuroscience

Cognitive Neuroscience

English

Granulin Knock Out Zebrafish Lack Frontotemporal Lobar Degeneration and Neuronal Ceroid Lipofuscinosis Pathology

Multidisciplinary

English

The Alzheimer′s Disease-Associated Protective Plcγ2-P522r Variant Promotes Beneficial Microglial Functions

English

Fibrillar Aβ Triggers Microglial Proteome Alterations and Dysfunction in Alzheimer Mouse Models

English

Intramembrane Cleavage of TREM2 Is Determined by Its Intrinsic Structural Dynamics

English

Amyloid at the Cutting Edge: Activation of Α-Secretase Prevents Amyloidogenesis in an Alzheimer Disease Mouse Model

Journal of Clinical Investigation

English

A Novel Sorting Nexin Modulates Endocytic Trafficking and Α-Secretase Cleavage of the Amyloid Precursor Protein

Journal of Biological Chemistry

Molecular Biology

English

The Proteolytic Fragments of the Alzheimer’s Disease-Associated Presenilin-1 Form Heterodimers and Occur as a 100–150-kDa Molecular Mass Complex

Journal of Biological Chemistry

Molecular Biology

English