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Publications by David E. Root

The Bromodomain Protein Brd4 Insulates Chromatin From DNA Damage Signalling

Nature
Multidisciplinary
2013English

In Vivo Discovery of Immunotherapy Targets in the Tumour Microenvironment

Nature
Multidisciplinary
2014English

HIF Activation Causes Synthetic Lethality Between the VHL Tumor Suppressor and the EZH1 Histone Methyltransferase

Science Translational Medicine
Medicine
2017English

Synthetic Lethal Screening in the Mammalian Central Nervous System Identifies Gpx6 as a Modulator of Huntington’s Disease

Proceedings of the National Academy of Sciences of the United States of America
Multidisciplinary
2014English

A Functional Landscape of Resistance to MEK1/2 and CDK4/6 Inhibition in NRAS Mutant Melanoma

Cancer Research
Cancer ResearchOncology
2019English

The Master Regulator of the Cellular Stress Response (HSF1) Is Critical for Orthopoxvirus Infection

PLoS Pathogens
ImmunologyMolecular BiologyVirologyMicrobiologyParasitologyGenetics
2014English

Creation of Novel Protein Variants With CRISPR/Cas9-Mediated Mutagenesis: Turning a Screening By-Product Into a Discovery Tool

PLoS ONE
Multidisciplinary
2017English

Resources for the Design of CRISPR Gene Editing Experiments

Genome Biology
2015English

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