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Publications by David Gnutt

Inhibition of Huntingtin Exon-1 Aggregation by the Molecular Tweezer CLR01

Journal of the American Chemical Society

Surface Chemistry

English

Spliceosomal U1A Protein-Sl2 RNA Binding Affinity Decreases in Cells

Biophysical Journal

English

Related publications

The Molecular Tweezer CLR01 Stabilizes a Disordered Protein-Protein Interface

English

Polyglutamine Disruption of the Huntingtin Exon 1 N Terminus Triggers a Complex Aggregation Mechanism

Nature Structural and Molecular Biology

Structural Biology

Molecular Biology

English

The Molecular Tweezer CLR01 Inhibits Aberrant Superoxide Dismutase 1 (SOD1) Self-Assembly in Vitro and in the G93a-Sod1 Mouse Model of ALS

Journal of Biological Chemistry

Molecular Biology

English

The Presence of Mitochondria Influences Huntingtin Aggregation

Biophysical Journal

English

Emerging Β-Sheet Rich Conformations in Supercompact Huntingtin Exon-1 Mutant Structures

Journal of the American Chemical Society

Surface Chemistry

English

Cellular Inclusion Bodies of Mutant Huntingtin Exon 1 Obscure Small Fibrillar Aggregate Species

Scientific Reports

Multidisciplinary

English

The Predicted Structure of the Headpiece of the Huntingtin Protein and Its Implications on Huntingtin Aggregation

Journal of Molecular Biology

Structural Biology

Molecular Biology

English

Inhibition of Aggregation of Mutant Huntingtin by Nucleic Acid Aptamers in Vitro and in a Yeast Model of Huntington’s Disease

English

Noninvasive Measurement of Protein Aggregation by Mutant Huntingtin Fragments or Α-Synuclein in the Lens

Journal of Biological Chemistry

Molecular Biology

English