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Publications by David P. Lane

Drugging the P53 Pathway: Understanding the Route to Clinical Efficacy

Nature Reviews Drug Discovery
MedicineDrug DiscoveryPharmacology
2014English

P53 Isoforms Regulate Aging- And Tumor-Associated Replicative Senescence in T Lymphocytes

Journal of Clinical Investigation
Medicine
2013English

Autophagic Degradation of the Inhibitory P53 Isoform Δ133p53α as a Regulatory Mechanism for P53-Mediated Senescence

Nature Communications
AstronomyGeneticsMolecular BiologyBiochemistryChemistryPhysics
2014English

A DHODH Inhibitor Increases P53 Synthesis and Enhances Tumor Cell Killing by P53 Degradation Blockage

Nature Communications
AstronomyGeneticsMolecular BiologyBiochemistryChemistryPhysics
2018English

Inhibiting P53 Acetylation Reduces Cancer Chemotoxicity

Cancer Research
Cancer ResearchOncology
2017English

Stereoisomerism of Stapled Peptide Inhibitors of the P53-Mdm2 Interaction: An Assessment of Synthetic Strategies and Activity Profiles

Chemical Science
Chemistry
2019English

Lipids Shape the Electron Acceptor-Binding Site of the Peripheral Membrane Protein Dihydroorotate Dehydrogenase

Cell Chemical Biology
Molecular MedicineMolecular BiologyPharmacologyBiochemistryClinical BiochemistryDrug Discovery
2018English

Functionalized Resins for the Synthesis of Peptide Alcohols

Chemistry - A European Journal
Organic ChemistryCatalysisChemistry
2019English

Long Range Recognition and Selection in IDPs: The Interactions of the C-Terminus of P53

Scientific Reports
Multidisciplinary
2016English

Crystallization of eIF4E Complexed With eIF4GI Peptide and Glycerol Reveals Distinct Structural Differences Around the Cap-Binding Site

Cell Cycle
MedicineDevelopmental BiologyCell BiologyMolecular Biology
2010English

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