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A 12-Month Oral Repeated Dose Toxicity Study of (±)-4-Diethylamino-1, 1-Dimethylbut-2-Yn-1-Yl 2-Cyclohexyl-2-Hydroxy-2-Phenylacetate Monohydrochloride Monohydrate (Ns-21), a Novel Drug for Urinary Frequency and Incontinence, in Dogs Followed by a 2-Month Recovery Test